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Hariklia Hatzissevastou-Loukidou, M. D. , Theodora G. Kalemi, M. Sc

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Presentation on theme: "Hariklia Hatzissevastou-Loukidou, M. D. , Theodora G. Kalemi, M. Sc"— Presentation transcript:

1 Characterization of a de novo balanced 1;Y translocation in a phenotypically normal twin male infant 
Hariklia Hatzissevastou-Loukidou, M.D., Theodora G. Kalemi, M.Sc., Alexandros F. Lambropoulos, Ph.D., Maria Nikita, M.D., Ellada Sotiridou, M.D., Basil C. Tarlatzis, M.D., Alexandros Kotsis, M.D.  Fertility and Sterility  Volume 85, Issue 4, Pages 1059.e e7 (April 2006) DOI: /j.fertnstert Copyright © 2006 American Society for Reproductive Medicine Terms and Conditions

2 FIGURE 1 (A) Partial karyotype (G banding) and (B) ideogram of the de novo t(1;Y). Vertical arrows indicate the translocation breakpoints. Horizontal arrows indicate the derived Y chromosome. Hatzissevastou-Loukidou. De novo balanced 1;Y translocation. Fertil Steril 2006. Fertility and Sterility  , 1059.e e7DOI: ( /j.fertnstert ) Copyright © 2006 American Society for Reproductive Medicine Terms and Conditions

3 FIGURE 2 Agarose gel electrophoresis of PCR showing integrity of Yp (TSPY) and absence of microdeletions in regions AZFa, AZFb, AZFc, and distal AZFc (positive amplification of four STSs). L = molecular weight ladder; C− = control female; C+ = control fertile male; 1 = patient. Hatzissevastou-Loukidou. De novo balanced 1;Y translocation. Fertil Steril 2006. Fertility and Sterility  , 1059.e e7DOI: ( /j.fertnstert ) Copyright © 2006 American Society for Reproductive Medicine Terms and Conditions


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