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Volume 64, Issue 4, Pages (October 2003)

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Presentation on theme: "Volume 64, Issue 4, Pages (October 2003)"— Presentation transcript:

1 Volume 64, Issue 4, Pages 1495-1504 (October 2003)
Increased albumin and fibrinogen synthesis rate in patients with chronic renal failure  Berthil H.C.M.T. Prinsen, Ton J. Rabelink, Jaap J. Beutler, George A. Kaysen, Jose De Boer, Walther H. Boer, E. Christiaan Hagen, Ruud Berger, Monique G.M. De Sain-Van Der Velden  Kidney International  Volume 64, Issue 4, Pages (October 2003) DOI: /j x Copyright © 2003 International Society of Nephrology Terms and Conditions

2 Figure 1 Model for estimation of albumin and fibrinogen fractional synthesis rates (FSR) for patients and control subjects. Compartment 1 represents the precursor pool and compartment 2 represents the plasma albumin or fibrinogen pool. The k-value represents the rate constant. The equation used for calculation of FSR_day = k (2,1) × 24 × 100; 24 is the conversion of pools/hour to pools/day; 100 is the conversion of pools to %. Kidney International  , DOI: ( /j x) Copyright © 2003 International Society of Nephrology Terms and Conditions

3 Figure 2 Relationship between absolute synthesis rate (ASR) of fibrinogen (mg/kg/day) and the ASR of albumin (mg/kg/day) for predialysis patients (N = 6) (▪), peritoneal dialysis patients (N = 7) (▴), and control subjects (N = 8) (•). The 95% confidence limits of the entire group are shown on either side of the regression line (r2 = 0.665, P < , N = 21). Kidney International  , DOI: ( /j x) Copyright © 2003 International Society of Nephrology Terms and Conditions


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