1. Deceased solid organ donors Recent trends from ANZOD
Stephen McDonald

2. Aims
Review recent changes in deceased donor numbers & rates by different metrics
Highlight trends in donor characteristics
Consider how these will affect potential future recipients

3. Donor numbers

4. Population

5. Donor rates

6. Brain vs circulatory death

7. Donor ages

8. Age-specific donor rates

9. Deaths as denominator

10. Population death rates
Age-standardised death rate, Australia, ABS 33020

11. Age-specific donor rates by death rate

12. Cause of death

13. Age and cause of death

14. Proportion who are kidney donors

15. Donor age and organs utilised

16. Donor comorbidities

17. Donor comorbidities

18. Donor comorbidities

19. Kidney function at donation

20. Kidney biopsy Kidney(s) not utilised Kidney(s) transplanted Total
Retrieval biopsy
47 (67%)
464 (14%)
511
No retrieval biopsy
23 (33%)
2800 (86%)
2823 70
3264
3334
All utilised donors, Australia and New Zealand.

21. Kidney function

22. Outcome predictors

23. Outcome predictors
Explanatory power of multivariate Cox model for graft failure for recipients , Australia and New Zealand

24. Summary Profound changes in donor rates
50-59 and rate per deaths have doubled over past 6-7 years
Steady increase in rate among younger donors
Predominantly “medical” rather than traumatic causes of death
Metric is important
Population is rising faster than number of deaths=falling death rate

25. Summary DCD a major component of increase
Increase seen across all age groups
In absolute terms, increase greatest in year age groups
Older donors, more “medical” donors
Almost 10% of donors have diabetes, and 20% hypertension
Age of donor (rather than cause of death) is the key factor in outcomes
Use of biopsies is uncommon, but associated with a much higher chance of non-utilisation.

26. Time to donation
Median number of days from admission to donation =2

27. Age by organs retrieved

28. Age/gender over time