Presentation is loading. Please wait.

Presentation is loading. Please wait.

Cardiomyocyte apoptosis and ischemic preconditioning in open heart operations  Zhong-Kai Wu, MD, PhD, Jari Laurikka, MD, PhD, Antti Saraste, MD, PhD, Ville.

Published byJuha-Pekka Ketonen Modified over 5 years ago

Similar presentations

Presentation on theme: "Cardiomyocyte apoptosis and ischemic preconditioning in open heart operations  Zhong-Kai Wu, MD, PhD, Jari Laurikka, MD, PhD, Antti Saraste, MD, PhD, Ville."— Presentation transcript:

1 Cardiomyocyte apoptosis and ischemic preconditioning in open heart operations 
Zhong-Kai Wu, MD, PhD, Jari Laurikka, MD, PhD, Antti Saraste, MD, PhD, Ville Kytö, MB, Erkki J Pehkonen, MD, PhD, Timo Savunen, MD, PhD, Matti R Tarkka, MD, PhD  The Annals of Thoracic Surgery  Volume 76, Issue 2, Pages (August 2003) DOI: /S (03)

2 Fig 1 Cardiac index (CI) in coronary artery bypass grafting (CABG) patients. Ischemic preconditioning (dotted line) significantly improved postoperative CI recovery (p = 0.036, analysis of variance for repeated measures). (POD = postoperative day.) The Annals of Thoracic Surgery  , DOI: ( /S (03) )

3 Fig 2 Right ventricular ejection fraction (RVEF) in coronary artery bypass grafting (CABG) patients. Ischemic preconditioning (dotted line) significantly improved postoperative RVEF recovery (p = 0.001, analysis of variance for repeated measures). (POD = postoperative day.) The Annals of Thoracic Surgery  , DOI: ( /S (03) )

4 Fig 3 A TUNEL-positive cardiomyocyte in a sample obtained during reperfusion after cardiopulmonary bypass. (A) The positive TUNEL reaction is visible as a dark staining in the nucleus (black arrow). (B) Immunohistochemical staining of the same cell with an antibody to cardiac myosin demonstrates the cardiomyocyte origin of the cell (white arrow). The Annals of Thoracic Surgery  , DOI: ( /S (03) )

5 Fig 4 Cardiac troponin I (CTnI) in coronary artery bypass grafting (CABG) patients. Cardioplegic ischemia and reperfusion significantly increased serum CTnI release. Similar amounts of CTnI were found in ischemic preconditioning (dotted line) and control (straight line) patients. (POD = postoperative day.) The Annals of Thoracic Surgery  , DOI: ( /S (03) )

6 Fig 5 Creatine kinase isoenzyme MB (CK-MB) in coronary artery bypass grafting (CABG) patients. Cardioplegic ischemia and reperfusion significantly increased serum cardiac tropinin I release. Similar amounts of CK-MB were found in ischemic preconditioning (dotted line) and control (straight line) patients. (POD = postoperative day.) The Annals of Thoracic Surgery  , DOI: ( /S (03) )

Download ppt "Cardiomyocyte apoptosis and ischemic preconditioning in open heart operations  Zhong-Kai Wu, MD, PhD, Jari Laurikka, MD, PhD, Antti Saraste, MD, PhD, Ville."

Similar presentations

Measurement of troponin T to detect cardioprotective effect of trimetazidine during coronary artery bypass grafting  Bülent Tünerir, MD, Ömer Çolak, MD,

Measurement of troponin T to detect cardioprotective effect of trimetazidine during coronary artery bypass grafting  Bülent Tünerir, MD, Ömer Çolak, MD,
Results of Coronary Artery Endarterectomy and Coronary Artery Bypass Grafting for Diffuse Coronary Artery Disease  Srikrishna Sirivella, MD, Isaac Gielchinsky,

Results of Coronary Artery Endarterectomy and Coronary Artery Bypass Grafting for Diffuse Coronary Artery Disease  Srikrishna Sirivella, MD, Isaac Gielchinsky,
Stem Cell Engraftment and Survival in the Ischemic Heart

Stem Cell Engraftment and Survival in the Ischemic Heart
Effect of intravenous N-acetylcysteine on outcomes after coronary artery bypass surgery: A randomized, double-blind, placebo-controlled clinical trial 

Effect of intravenous N-acetylcysteine on outcomes after coronary artery bypass surgery: A randomized, double-blind, placebo-controlled clinical trial 
Cardiomyocyte apoptosis and ischemic preconditioning in open heart operations  Zhong-Kai Wu, MD, PhD, Jari Laurikka, MD, PhD, Antti Saraste, MD, PhD, Ville.

Cardiomyocyte apoptosis and ischemic preconditioning in open heart operations  Zhong-Kai Wu, MD, PhD, Jari Laurikka, MD, PhD, Antti Saraste, MD, PhD, Ville.
Coronary Artery Bypass for Heart Failure in Ischemic Cardiomyopathy: 17-Year Follow- Up  Marco Pocar, MD, PhD, Andrea Moneta, MD, Adalberto Grossi, MD,

Coronary Artery Bypass for Heart Failure in Ischemic Cardiomyopathy: 17-Year Follow- Up  Marco Pocar, MD, PhD, Andrea Moneta, MD, Adalberto Grossi, MD,
Leena Khaitan, MD, Francis P Sutter, Scott M Goldman, MD 

Leena Khaitan, MD, Francis P Sutter, Scott M Goldman, MD 
Long-Term Outcome of Coronary Artery Bypass Grafting in Patients With Left Ventricular Dysfunction  Paolo Nardi, MD, PhD, Antonio Pellegrino, MD, Antonio.

Long-Term Outcome of Coronary Artery Bypass Grafting in Patients With Left Ventricular Dysfunction  Paolo Nardi, MD, PhD, Antonio Pellegrino, MD, Antonio.
Revascularization of severe hibernating myocardium in the beating heart: early hemodynamic and metabolic features  Evasio Pasini, MD, Gianna Ferrari,

Revascularization of severe hibernating myocardium in the beating heart: early hemodynamic and metabolic features  Evasio Pasini, MD, Gianna Ferrari,
Salah Sabbagh, MD, Michele M. Henry Salzman, BS, Robert A

Salah Sabbagh, MD, Michele M. Henry Salzman, BS, Robert A
Coronary artery bypass grafting in patients with advanced left ventricular dysfunction  Gregory D Trachiotis, MD, William S Weintraub, MD, Thomas S Johnston,

Coronary artery bypass grafting in patients with advanced left ventricular dysfunction  Gregory D Trachiotis, MD, William S Weintraub, MD, Thomas S Johnston,
Effect of intravenous N-acetylcysteine on outcomes after coronary artery bypass surgery: A randomized, double-blind, placebo-controlled clinical trial 

Effect of intravenous N-acetylcysteine on outcomes after coronary artery bypass surgery: A randomized, double-blind, placebo-controlled clinical trial 
Long-Term Consequences of Postoperative Heart Failure After Surgery for Aortic Stenosis Compared With Coronary Surgery  Farkas B. Vánky, MD, PhD, Erik.

Long-Term Consequences of Postoperative Heart Failure After Surgery for Aortic Stenosis Compared With Coronary Surgery  Farkas B. Vánky, MD, PhD, Erik.
Long-Term Survival of Patients With Ischemic Cardiomyopathy Treated by Coronary Artery Bypass Grafting Versus Medical Therapy  Eric J. Velazquez, MD,

Long-Term Survival of Patients With Ischemic Cardiomyopathy Treated by Coronary Artery Bypass Grafting Versus Medical Therapy  Eric J. Velazquez, MD,
Juan A. Crestanello, MD, Richard C. Daly, MD 

Juan A. Crestanello, MD, Richard C. Daly, MD 
Coronary artery operation in patients after breast cancer therapy

Coronary artery operation in patients after breast cancer therapy
Cardiac troponin I release after open heart surgery: a marker of myocardial protection?  Emmanuelle Vermes, MD, Martine Mesguich, MD, Rémi Houel, MD, Céline.

Cardiac troponin I release after open heart surgery: a marker of myocardial protection?  Emmanuelle Vermes, MD, Martine Mesguich, MD, Rémi Houel, MD, Céline.
Comparison of troponin-I and troponin-T after pediatric cardiovascular operation  Franz F Immer, MD, Franco P Stocker, MD, Andrea M Seiler, MD, Jean-Pierre.

Comparison of troponin-I and troponin-T after pediatric cardiovascular operation  Franz F Immer, MD, Franco P Stocker, MD, Andrea M Seiler, MD, Jean-Pierre.
François Dagenais, MD, L.Conrad Pelletier, MD, Michel Carrier, MD 

François Dagenais, MD, L.Conrad Pelletier, MD, Michel Carrier, MD 
Ineffectiveness and potential proarrhythmia of atrial pacing for atrial fibrillation prevention after coronary artery bypass grafting  Mina K Chung, MD,

Ineffectiveness and potential proarrhythmia of atrial pacing for atrial fibrillation prevention after coronary artery bypass grafting  Mina K Chung, MD,

Similar presentations

Ads by Google