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A Targeted View Cell Volume 153, Issue 6, (June 2013)

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Presentation on theme: "A Targeted View Cell Volume 153, Issue 6, (June 2013)"— Presentation transcript:

1 A Targeted View Cell Volume 153, Issue 6, (June 2013)
Cell  Volume 153, Issue 6, (June 2013) DOI: /j.cell Copyright © Terms and Conditions

2 The mTOR FRB domain (red) restricts access to the kinase domain (pink) and has a dual substrate recruitment/rapamycin-binding site (green). Image courtesy of N. Pavletich. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions

3 Structure of the human smoothened receptor, critical in embryonic development. Image generated by Katya Kadyshevskaya, Stevens Laboratory, TSRI. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions

4 X-ray structure of the potent and selective inhibitor WEHI-539 bound to the canonical hydrophobic groove of BCL-XL. Image courtesy of G. Lessene and P. Czabotar. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions

5 A molecule of AGI-6780 binds at the dimer interface of mutant IDH2 (R140Q). Image courtesy of Eric D. Smith. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions


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