Presentation is loading. Please wait.

Presentation is loading. Please wait.

SENP2 overexpression increases FAO by upregulating expression of FAO-associated enzymes in muscle. SENP2 overexpression increases FAO by upregulating expression.

Similar presentations


Presentation on theme: "SENP2 overexpression increases FAO by upregulating expression of FAO-associated enzymes in muscle. SENP2 overexpression increases FAO by upregulating expression."— Presentation transcript:

1 SENP2 overexpression increases FAO by upregulating expression of FAO-associated enzymes in muscle.
SENP2 overexpression increases FAO by upregulating expression of FAO-associated enzymes in muscle. A–C: WT and mSENP2-TG (TG) mice were fed with chow or HFD for 12 weeks. The levels of free fatty acids (FFA) (A), triglycerides (B), and FAO (C) in their gastrocnemius muscle were determined (n = 8/group). D and E: Total mRNAs were isolated from the muscles of the mice and subjected to real-time PCR (n = 10–14/group) using primers for FAO-associated enzymes (D) and PPARs and PGC1α (E). The mRNA level seen in chow-fed WT mice muscle was expressed as 1.0, and the others were expressed as its relative values. Data are the mean ± SEM. *P < 0.05 compared with WT mice. Young Do Koo et al. Diabetes 2015;64: ©2015 by American Diabetes Association


Download ppt "SENP2 overexpression increases FAO by upregulating expression of FAO-associated enzymes in muscle. SENP2 overexpression increases FAO by upregulating expression."

Similar presentations


Ads by Google