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Postischemic hyperthermia exacerbates neurologic injury after deep hypothermic circulatory arrest  Dominique Shum-Tim, MDa, Mitsugi Nagashima, MDa, Toshiharu.

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Presentation on theme: "Postischemic hyperthermia exacerbates neurologic injury after deep hypothermic circulatory arrest  Dominique Shum-Tim, MDa, Mitsugi Nagashima, MDa, Toshiharu."— Presentation transcript:

1 Postischemic hyperthermia exacerbates neurologic injury after deep hypothermic circulatory arrest 
Dominique Shum-Tim, MDa, Mitsugi Nagashima, MDa, Toshiharu Shinoka, MDa, Jan Bucerius, MDa, Georg Nollert, MDa, Hart G. W. Lidov, MDb, Adre du-Plessis, MDc, Peter C. Laussen, MDd, Richard A. Jonas, MDa  The Journal of Thoracic and Cardiovascular Surgery  Volume 116, Issue 5, Pages (November 1998) DOI: /S (98) Copyright © 1998 Mosby, Inc. Terms and Conditions

2 Fig 1 Representative electroencephalographic tracing of seizure in a group III hyperthermic animal. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

3 Fig 2 Mean electroencephalographic amplitude at baseline and at 14 and 48 hours after the operation. *P < .05, group I versus group III. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

4 Fig 3 Results of cerebral oxyhemoglobin level by NIRS examination. DPF, Differential path length factor. *P < .05, group I versus group III. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

5 Fig 4 Results of cerebral deoxyhemoglobin level by NIRS examination. DPF, Differential path length factor. *P < .05, group I versus group III. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

6 Fig 5 Results of cytochrome aa3 level by NIRS examination. DPF, Differential path length factor. *P < .05, group I versus group III. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

7 Fig 6 NDS on PODs 2, 3, and 4. *P < .05, group I versus group III.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

8 Fig 7 OPC on PODs 2, 3, and 4. *P < .05, group I versus group III.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

9 Fig 8 Histologic scores for neocortex, hippocampus, dentate gyrus, and caudate nucleus. *P < .05, group I versus group III. #P < .05, group II versus group III. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

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