1. Effect of Id1 deletion on insulin action in wild-type and Id1−/− mice fed a chow diet (white triangle/striped bar and black triangle/hatched bar, respectively) or a high-fat diet (white square/white bar and black square/black bar, respectively).
Effect of Id1 deletion on insulin action in wild-type and Id1−/− mice fed a chow diet (white triangle/striped bar and black triangle/hatched bar, respectively) or a high-fat diet (white square/white bar and black square/black bar, respectively). A: Blood glucose levels during an intraperitoneal ITT of wild-type (n = 5) and Id1−/− (n = 4) mice fed a chow diet and wild-type (n = 8) and Id1−/− (n = 6) mice fed a high-fat diet. ANOVA: P < 0.05 for effect of fat diet in wild-type and Id1−/− mice. B: AUC 0–30 min of blood glucose levels during intraperitoneal ITT. *P < 0.05 for effect of diet in wild-type and Id1−/− mice.
Mia C. Åkerfeldt, and D. Ross Laybutt Diabetes 2011;60:
©2011 by American Diabetes Association