1. Herpesviridae
Part II

11. Cytomegalic inclusion disease(CID)

15. تشخیص آزمایشگاهی کشت سلول: کمتر کاربرد دارد. سرولوژی
تشخیص آنتی ژن ویروس
PCR

19. HHV6 pathogenesis

20. HHV6 typically occur in early childhood.
primary infection causes exanthem subitum (roseola infantum, or "sixth disease")
the mild common childhood disease characterized by high fever and skin rash. The virus is associated with febrile seizures in children.
Infections persist for life. Reactivation appears to be common in transplant patients and during pregnancy.

21. Roseola

22. گاما هرپس ویرینه

23. Close contact

25. Infectious Mononucleosis

26. EBV Mono

27. Diagnosis of Epstein-Barr Virus
Symptoms
Mild headache, fatigue, fever
Triad: Lymphadenopathy, splenomegaly, exudative pharyngitis
Other: Hepatitis, ampicillin-induced rash
Complete blood cell count
Hyperplasia
Atypical lymphocytes (Downey cells) (T cells)
Heterophile antibody (transient)
EBV-antigen specific antibody

29. Oral Hairy Leukoplakia
This lesion is a wart-like growth that develops on the tongue in some HIV-infected persons and transplant patients.
It is an epithelial focus of EBV replication.

30. Burkitt's Lymphoma
EBV is associated with the development of Burkitt's lymphoma (a tumor of the jaw in African children and young adults).

32. Nasopharyngeal Carcinoma
This cancer of epithelial cells is common in males of Chinese origin.

33. Lymphoproliferative Diseases in Immunodeficient Hosts
Immunodeficient patients are susceptible to EBV-induced lymphoproliferative diseases that may be fatal.
From 1% to 10% of transplant patients develop an EBV-associated lymphoproliferative disorder, often when experiencing a primary infection.

35. HHV8
Kaposi’s sarcoma Herpes Virus (KSHV)