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m6A identification method based on m6A sensitive RNA endoribonuclease

Published byHeiko Keller Modified over 5 years ago

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Presentation on theme: "m6A identification method based on m6A sensitive RNA endoribonuclease"— Presentation transcript:

1 Fig. 1 m6A identification method based on m6A sensitive RNA endoribonuclease.
m6A identification method based on m6A sensitive RNA endoribonuclease. (A) Validation for the methylation sensitivity of endoribonuclease MazF by synthetic m6A-containing RNA oligonucleotide. (B) Validation for the methylation sensitivity of endoribonuclease ChpBK. (C) Various ratios of m6A-containing oligo mixed with unmethylated oligo digested by endoribonuclease. The m6A/A ratios of synthetic oligo are indicated to imitate practical RNAs with different m6A ratios. (D) Relative grayscale of proportionally mixed RNA oligo digested by endoribonuclease. (E) The schematic diagram of m6A-REF-seq. Zhang Zhang et al. Sci Adv 2019;5:eaax0250 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Fig. 5 Correlation of RNA expression and protein abundance.

Fig. 5 Correlation of RNA expression and protein abundance.
Fig. 2 Transport properties of a BP transistor at low temperature.

Fig. 2 Transport properties of a BP transistor at low temperature.
Fig. 4 Ballistic simulation of BP FETs.

Fig. 4 Ballistic simulation of BP FETs.
Fig. 2 Global production, use, and fate of polymer resins, synthetic fibers, and additives (1950 to 2015; in million metric tons). Global production, use,

Fig. 2 Global production, use, and fate of polymer resins, synthetic fibers, and additives (1950 to 2015; in million metric tons). Global production, use,
Vibrational spectra of medieval human bones (Leopoli-Cencelle, Italy)

Vibrational spectra of medieval human bones (Leopoli-Cencelle, Italy)
Fig. 3 Projected gains in MCP.

Fig. 3 Projected gains in MCP.
Fig. 3 Oil, gas, and FP water variations with time.

Fig. 3 Oil, gas, and FP water variations with time.
Fig. 5 Thermal conductivity of n-type ZrCoBi-based half-Heuslers.

Fig. 5 Thermal conductivity of n-type ZrCoBi-based half-Heuslers.
Fig. 1 Map of water stress and shale plays.

Fig. 1 Map of water stress and shale plays.
Fig. 1 Examples of experimental stimuli and behavioral performance.

Fig. 1 Examples of experimental stimuli and behavioral performance.
Fig. 1 Wireless, battery-free neural cuff for programmable pharmacology and optogenetics. Wireless, battery-free neural cuff for programmable pharmacology.

Fig. 1 Wireless, battery-free neural cuff for programmable pharmacology and optogenetics. Wireless, battery-free neural cuff for programmable pharmacology.
Fig. 3 Electron PSD in various regions.

Fig. 3 Electron PSD in various regions.
Fig. 2 Some examples of weekly forecasts (the number of the forecasts are reported on Table 1). Some examples of weekly forecasts (the number of the forecasts.

Fig. 2 Some examples of weekly forecasts (the number of the forecasts are reported on Table 1). Some examples of weekly forecasts (the number of the forecasts.
Fig. 4 Resynthesized complex boronic acid derivatives based on different scaffolds on a millimole scale and corresponding yields. Resynthesized complex.

Fig. 4 Resynthesized complex boronic acid derivatives based on different scaffolds on a millimole scale and corresponding yields. Resynthesized complex.
Fig. 6 Comparison of properties of water models.

Fig. 6 Comparison of properties of water models.
Single-base validation using ligation-amplification method and qPCR

Single-base validation using ligation-amplification method and qPCR
Fig. 1 Mean and median RCR (Relative Citation Ratio) of Roadmap Epigenomics Program research articles for each year. Mean and median RCR (Relative Citation.

Fig. 1 Mean and median RCR (Relative Citation Ratio) of Roadmap Epigenomics Program research articles for each year. Mean and median RCR (Relative Citation.
Fig. 2 Reference-fixing experiment, results.

Fig. 2 Reference-fixing experiment, results.
Fig. 2 Transcriptome-wide distribution of m6A revealed by m6A-REF-seq.

Fig. 2 Transcriptome-wide distribution of m6A revealed by m6A-REF-seq.
Fig. 5 Conservation of m6A in mammals.

Fig. 5 Conservation of m6A in mammals.

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