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Confocal laser endomicroscopy reliably detects sepsis-related and treatment-associated changes in intestinal mucosal microcirculation  C. Schmidt, C.

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Presentation on theme: "Confocal laser endomicroscopy reliably detects sepsis-related and treatment-associated changes in intestinal mucosal microcirculation  C. Schmidt, C."— Presentation transcript:

1 Confocal laser endomicroscopy reliably detects sepsis-related and treatment-associated changes in intestinal mucosal microcirculation  C. Schmidt, C. Lautenschläger, B. Petzold, Y. Sakr, G. Marx, A. Stallmach  British Journal of Anaesthesia  Volume 111, Issue 6, Pages (December 2013) DOI: /bja/aet219 Copyright © 2013 The Author(s) Terms and Conditions

2 Fig 1 Time course of the animal model of septic shock.
British Journal of Anaesthesia  , DOI: ( /bja/aet219) Copyright © 2013 The Author(s) Terms and Conditions

3 Fig 2 Representative images of the mucosa of the gastric antrum (a), duodenum (b), and rectum (c) obtained by cLE after administration of FITC-labelled dextran before (left panel) and after (right panel) detection of mucosal vessels by the image detection software for quantitative analysis. British Journal of Anaesthesia  , DOI: ( /bja/aet219) Copyright © 2013 The Author(s) Terms and Conditions

4 Fig 3 The quantitative assessment of mucosal microvessels in different parts of the GI tract: (a) total vessel length; (b) mean capillary diameter; and (c) FCD [mean values (1 sd)]. British Journal of Anaesthesia  , DOI: ( /bja/aet219) Copyright © 2013 The Author(s) Terms and Conditions

5 Fig 4 Uncoupling of MAP and FCD in different parts of the GI tract (a, stomach; b, duodenum; c, ileum; d, rectum) at baseline (triangle), during septic shock (circle), and after volume therapy (square). Arrows indicate the sequence of measurements. British Journal of Anaesthesia  , DOI: ( /bja/aet219) Copyright © 2013 The Author(s) Terms and Conditions


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