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PGC-1α isoforms. PGC-1α isoforms. A, The illustration of PGC-1α new alternative exons and known exons in RefSeq/Ensembl/UCSC genome references. Human ESTs.

Published byTeresa Porter Modified over 5 years ago

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Presentation on theme: "PGC-1α isoforms. PGC-1α isoforms. A, The illustration of PGC-1α new alternative exons and known exons in RefSeq/Ensembl/UCSC genome references. Human ESTs."— Presentation transcript:

1 PGC-1α isoforms. PGC-1α isoforms. A, The illustration of PGC-1α new alternative exons and known exons in RefSeq/Ensembl/UCSC genome references. Human ESTs and mouse TSS with enhancer signals derived from >1000 human and mouse primary cells, cell lines, and tissues were mapped using CAGE. B, Diagram and PCR products show four different PGC-1α isoforms from SH-SY5Y and mouse brain and heart. C, RT-PCR for four PGC-1α isoforms, SDHA, Tomm20, and GAPDH RNA 4 weeks after stereotactic delivery of AAV-GFP or AAV-Cre-GFP into PGC-1αflox/flox mice; n = 3/group. D, Quantification of C normalized to GAPDH; n = 3/group. *p < 0.05, **p < Haisong Jiang et al. eneuro 2016;3:ENEURO ©2016 by Society for Neuroscience

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