1. Primary immunodeficiency: Looking backwards, looking forwards
William T Shearer, MD, PhD, Charlotte Cunningham-Rundles, MD, PhD, Hans D Ochs, MD 
Journal of Allergy and Clinical Immunology 
Volume 113, Issue 4, Pages (April 2004)
DOI: /j.jaci

2. Fig 1
Treatment of primary immunodeficiency: hopes for a safe passage. In the remarkably short span of 4 decades, treatment of patients with primary immunodeficiencies has progressed from gammaglobulin injections to gene therapy. This extraordinary accomplishment is illustrated by 2 families, one with a girl cured of disease who had been brought across the dangerous waters of chronic illness by the Good Ship Hope with supportive and specific treatments for immunodeficiency and the other with a boy still needing immunoreconstitution. The little girl beckons to the bereft family to take the journey to a better life.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )