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Prime and boosts with PBK001 vaccine provided 100% protection with low bacterial burden in organs. Prime and boosts with PBK001 vaccine provided 100% protection.

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Presentation on theme: "Prime and boosts with PBK001 vaccine provided 100% protection with low bacterial burden in organs. Prime and boosts with PBK001 vaccine provided 100% protection."— Presentation transcript:

1 Prime and boosts with PBK001 vaccine provided 100% protection with low bacterial burden in organs.
Prime and boosts with PBK001 vaccine provided 100% protection with low bacterial burden in organs. (A) C57BL/6 mice were i.n. immunized with either PBS (n = 10) or strain PBK001 at 1.5 × 104 CFU (n = 10). Three weeks after the last boost, the mice were challenged with B. pseudomallei K96243 strain via the aerosol route. Survival was analyzed using a log rank (Kaplan Meier) test (****, P < ). (B) Bacterial burden in lungs, livers, and spleens (n = 7) of surviving mice at day 27 postchallenge. n.s., not significant. Nittaya Khakhum et al. mSphere 2019; doi: /mSphere

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