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Exposure to cow’s milk during the first 3 months of life is associated with increased levels of IgG subclass antibodies to β-lactoglobulin to 8 years 

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Presentation on theme: "Exposure to cow’s milk during the first 3 months of life is associated with increased levels of IgG subclass antibodies to β-lactoglobulin to 8 years "— Presentation transcript:

1 Exposure to cow’s milk during the first 3 months of life is associated with increased levels of IgG subclass antibodies to β-lactoglobulin to 8 years  Maria C. Jenmalm, MSc, Bengt Björkstén, MD, PhD  Journal of Allergy and Clinical Immunology  Volume 102, Issue 4, Pages (October 1998) DOI: /S (98) Copyright © 1998 Mosby, Inc. Terms and Conditions

2 Fig. 1 Levels (AUs) of IgG (A), IgG1 (B) and IgG4 (C) antibodies to β-lactoglobulin at birth, 6 months, 18 months, and 8 years. The 10th, 25th, 50th, 75th, and 90th percentiles and the outliers are indicated. Journal of Allergy and Clinical Immunology  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

3 Fig. 2 Levels (AUs) of IgG1 (A-C) and IgG4 (D-F) antibodies to β-lactoglobulin at 6 months, 18 months, and 8 years. The data are grouped according to age at exposure to cow’s milk (before or after the first 3 months of life). Note differences in scale. The 10th, 25th, 50th, 75th, and 90th percentiles and the outliers are indicated. Journal of Allergy and Clinical Immunology  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

4 Fig. 3 Levels (AUs) of IgG antibodies at 8 years of age in children with and without a maternal history of atopy (A). IgG4 antibody levels at 8 years in children with and without allergic symptoms and sensitization to allergens (B). The 10th, 25th, 50th, 75th, and 90th percentiles and the outliers are indicated. Journal of Allergy and Clinical Immunology  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

5 Fig. 4 Levels (AUs) of IgG, IgG1 , and IgG4 antibodies to β-lactoglobulin in children who were exposed to cow’s milk at 6 months (A-C) and at 18 months in children who were exposed to cow’s milk during the first 3 months of life (D-F) in relation to atopic dermatitis. The 10th, 25th, 50th, 75th, and 90th percentiles and the outliers are indicated. Journal of Allergy and Clinical Immunology  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions


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