1. Evidence for increased expression of eotaxin and monocyte chemotactic protein-4 in atopic dermatitis 
Rame A. Taha, MDa, Eleanor M. Minshall, PhDa, Donald Y.M. Leung, MD, PhDb, Mark Boguniewicz, MDb, Andrew Luster, MD, PhDc, Shigeo Muro, MDa, Masdo Toda, MDa, Qutayba A. Hamid, MD, PhDa 
Journal of Allergy and Clinical Immunology 
Volume 105, Issue 5, Pages (May 2000)
DOI: /mai
Copyright © 2000 Mosby, Inc. Terms and Conditions

2. Fig. 1
A, Representative examples of ISH of eotaxin mRNA in epidermal layer (E) of skin obtained from subjects with chronic AD subjects with use of digoxigenin-labeled antisense probe (phase contrast; original magnification ×400). Also note that there were some eotaxin mRNA-labeled antisense probe positive cells within the subepithelial layer (arrow). B, Negative control from chronic AD subjects with use of digoxigenin-labeled sense probe.
Journal of Allergy and Clinical Immunology  , DOI: ( /mai )
Copyright © 2000 Mosby, Inc. Terms and Conditions

3. Fig. 2
Expression of eotaxin and MCP-4 mRNA within the epidermal cell layer. Specific antisense digoxigenin riboprobes were used to identify eotaxin and MCP-4 mRNA-positive cells in skin biopsy specimens from acute and chronic AD lesions, uninvolved AD skin, and normal skin by ISH. Results are expressed as the percentage positive cells of the total epidermal cell layer. Filled symbols, Data for individual patients.
Journal of Allergy and Clinical Immunology  , DOI: ( /mai )
Copyright © 2000 Mosby, Inc. Terms and Conditions

4. Fig. 3
Expression of eotaxin and MCP-4 mRNA within the subepithelial cell layer. Specific antisense digoxigenin riboprobes were used to identify eotaxin and MCP-4 mRNA-positive cells in skin biopsy specimens from acute and chronic AD lesions, uninvolved AD skin, and normal skin by ISH. Results are expressed as numbers of positive cells per HPF (0.202 cm2). Filled symbols, Data for individual patients.
Journal of Allergy and Clinical Immunology  , DOI: ( /mai )
Copyright © 2000 Mosby, Inc. Terms and Conditions

5. Fig. 4
Relationship between eotaxin expression within the epidermal cell layer and numbers of resident eosinophils in chronic (filled circles) and acute (filled squares) AD skin lesions and uninvolved skin from patients with AD (filled triangles). There was a significant positive association observed (r 2 = 0.84, P < .05).
Journal of Allergy and Clinical Immunology  , DOI: ( /mai )
Copyright © 2000 Mosby, Inc. Terms and Conditions