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Contribution of dust mite and cat specific IgE to total IgE: Relevance to asthma prevalence  Elizabeth A. Erwin, MD, Eva Rönmark, PhD, Kristin Wickens,

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Presentation on theme: "Contribution of dust mite and cat specific IgE to total IgE: Relevance to asthma prevalence  Elizabeth A. Erwin, MD, Eva Rönmark, PhD, Kristin Wickens,"— Presentation transcript:

1 Contribution of dust mite and cat specific IgE to total IgE: Relevance to asthma prevalence 
Elizabeth A. Erwin, MD, Eva Rönmark, PhD, Kristin Wickens, PhD, Matthew S. Perzanowski, PhD, David Barry, MB, FRACP, Bo Lundbäck, MD, PhD, Julian Crane, MB, FRACP, Thomas A.E. Platts-Mills, MD, PhD  Journal of Allergy and Clinical Immunology  Volume 119, Issue 2, Pages (February 2007) DOI: /j.jaci Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Total IgE levels among wheezing (shaded bars) and nonwheezing children (solid gray bars) living in northern Sweden and New Zealand (n for each group in italics below the plots). Titers of IgE ranging from the lower to upper quartiles are represented in boxes; whisker plots include values from the 10th to 90th percentiles. Horizontal lines show the median. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 Specific IgE antibody titers in northern Sweden (A) and New Zealand (B). Data are the prevalence of children having a specific IgE antibody measurement in increasing ranges. Wheezing and nonwheezing children in each country are shown separately in figures marked i and ii, respectively. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4 Fig 3 Specific IgE antibody to cat and dust mite as a percentage of total IgE among children with high total IgE (≥200 IU/mL) living in New Zealand (n = 87) and Sweden (n = 105). Number of children making a specific IgE antibody response to each allergen is given in italics below each plot. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5 Fig 4 The relationship between specific IgE antibody and high total IgE (≥200 IU/mL) is shown for dust mite in New Zealand (A) and cat in northern Sweden (B). Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

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