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Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure  Susan Colilla, PhDa*, Dan Nicolae, PhDb, Anna Pluzhnikov,

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Presentation on theme: "Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure  Susan Colilla, PhDa*, Dan Nicolae, PhDb, Anna Pluzhnikov,"— Presentation transcript:

1 Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure 
Susan Colilla, PhDa*, Dan Nicolae, PhDb, Anna Pluzhnikov, PhDa, Malcolm N. Blumenthal, MDc, Terri H. Beaty, PhDd, Eugene R. Bleecker, MDe, Ethan M. Lange, PhDf, Stephen S. Rich, PhDf, Deborah A. Meyers, PhDe, Carole Ober, PhDa, Nancy J. Cox, PhDa  Journal of Allergy and Clinical Immunology  Volume 111, Issue 4, Pages (April 2003) DOI: /mai Copyright © 2003 Mosby, Inc. Terms and Conditions

2 Fig. 1 Schematic diagram of how affected individuals in a family were stratified into exposed and unexposed groups. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2003 Mosby, Inc. Terms and Conditions

3 Fig. 2 Results from genome-wide linkage analysis of asthma in CSGA white families on the basis of ETS exposure. The thick black line represents the lod scores from all asthmatic patients, the pink line is for exposed asthmatic patients, and the green line represents unexposed asthmatic patients. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2003 Mosby, Inc. Terms and Conditions

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