1. Low-dose conjugated equine estrogens elevate circulating neurotransmitters and improve the psychological well-being of menopausal women 
Arturo Zárate, M.D., Ph.D., Eugenia Fonseca, B.Sc., Raquel Ochoa, Lourdes Basurto, M.D., Marcelino Hernández, M.D. 
Fertility and Sterility 
Volume 77, Issue 5, Pages (May 2002)
DOI: /S (02)

2. FIGURE 1
Low-dose conjugated equine E (0.312 mg) significantly increased (P <.05) β-endorphin (upper panel). In contrast, noradrenaline (lower panel) decreased (P <.001) after 6 months of treatment.
Zárate. HRT improves psychological symptoms and neurotransmitters. Fertil Steril 2002.
Fertility and Sterility  , DOI: ( /S (02) )

3. FIGURE 2
Correlations between 17β-E2 and noradrenaline (upper panel) and 17β-E2 and β-endorphin (lower panel) levels were significant (P <.001).
Zárate. HRT improves psychological symptoms and neurotransmitters. Fertil Steril 2002.
Fertility and Sterility  , DOI: ( /S (02) )