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One-year follow-up of serum antimüllerian hormone levels in patients with cystectomy: are different sequential changes due to different mechanisms causing.

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Presentation on theme: "One-year follow-up of serum antimüllerian hormone levels in patients with cystectomy: are different sequential changes due to different mechanisms causing."— Presentation transcript:

1 One-year follow-up of serum antimüllerian hormone levels in patients with cystectomy: are different sequential changes due to different mechanisms causing damage to the ovarian reserve?  Atsuko Sugita, M.D., Akira Iwase, M.D., Maki Goto, M.D., Tatsuo Nakahara, M.D., Tomoko Nakamura, M.D., Mika Kondo, M.D., Satoko Osuka, M.D., Masahiko Mori, M.D., Ai Saito, M.D., Fumitaka Kikkawa, M.D.  Fertility and Sterility  Volume 100, Issue 2, Pages e3 (August 2013) DOI: /j.fertnstert Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 The serial changes in the serum AMH levels in each case in the decrease group (A) and the increase group (B) before surgery, 1 month after surgery, and 1 year after surgery. Fertility and Sterility  , e3DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Schematic illustrations of the hypothesis regarding the postoperative changes in the ovarian reserve after cystectomy for endometriomas. Fertility and Sterility  , e3DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

4 Supplemental Figure 1 The preoperative, 1-month, and 1-year postoperative serum AMH levels according to the number of removed follicles in the specimen. The open box and shaded box in each color show the serum AMH levels in the patients with <10 and ≥10 follicles in the specimens, respectively. The data are represented by box-and-whisker plots. The lines inside the boxes represent the median values, and the upper and lower limits of the boxes and whiskers indicate the interquartile and total ranges. The P values are represented by the italicized numbers. Fertility and Sterility  , e3DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

5 Supplemental Figure 2 The serial changes in the serum AMH levels in each case of laparoscopic myomectomy before surgery, 1 month after surgery, and 1 year after surgery. Fertility and Sterility  , e3DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

6 Supplemental Figure 3 Schematic illustrations of the rearrangements of the follicle cohort. Ovarian cystectomy possibly causes decreases in the number of AMH-producing follicles. Recruitment of primordial follicles to primary and small antral follicles may result in recovery of the serum AMH levels. Postoperative changes after cystectomy may cause decreases in the follicle cohort and thus a continuous decline of the serum AMH levels. Fertility and Sterility  , e3DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions


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