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Vitamin K for reversal of excessive vitamin K antagonist anticoagulation: a systematic review and meta-analysis by Rasha Khatib, Maja Ludwikowska, Daniel.

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Presentation on theme: "Vitamin K for reversal of excessive vitamin K antagonist anticoagulation: a systematic review and meta-analysis by Rasha Khatib, Maja Ludwikowska, Daniel."— Presentation transcript:

1 Vitamin K for reversal of excessive vitamin K antagonist anticoagulation: a systematic review and meta-analysis by Rasha Khatib, Maja Ludwikowska, Daniel M. Witt, Jack Ansell, Nathan P. Clark, Anne Holbrook, Wojtek Wiercioch, Holger Schünemann, and Robby Nieuwlaat BloodAdv Volume 3(5): March 12, 2019 © 2019 by The American Society of Hematology

2 All-cause mortality. −, low risk of bias; +, high risk of bias;
All-cause mortality. −, low risk of bias; +, high risk of bias; ?, unkown risk of bias; df, degree of freedom; M-H, Mantel Haenszel; trt, treatment. All-cause mortality. −, low risk of bias; +, high risk of bias; ?, unkown risk of bias; df, degree of freedom; M-H, Mantel Haenszel; trt, treatment. Rasha Khatib et al. Blood Adv 2019;3: © 2019 by The American Society of Hematology

3 Major bleeding. Major bleeding.
Rasha Khatib et al. Blood Adv 2019;3: © 2019 by The American Society of Hematology

4 Any thromboembolism event.
Rasha Khatib et al. Blood Adv 2019;3: © 2019 by The American Society of Hematology

5 Proportion of patients who reached goal INR values.
Rasha Khatib et al. Blood Adv 2019;3: © 2019 by The American Society of Hematology


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