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by David Deambrosis, Su Han Lum, Ryan M

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1 Immune cytopenia post–cord transplant in Hurler syndrome is a forme fruste of graft rejection
by David Deambrosis, Su Han Lum, Ryan M. Hum, Kay Poulton, Wendy Ogden, Simon Jones, Simon Stanworth, Denise Bonney, Prashant Hiwarkar, and Robert F. Wynn BloodAdv Volume 3(4): February 26, 2019 © 2019 by The American Society of Hematology

2 David Deambrosis et al. Blood Adv 2019;3:570-574
© 2019 by The American Society of Hematology

3 Risk factors for development of IMC
Risk factors for development of IMC. (A) Univariate analysis of risk factors for development of IMC after unrelated cord blood transplant for Hurler syndrome. Risk factors for development of IMC. (A) Univariate analysis of risk factors for development of IMC after unrelated cord blood transplant for Hurler syndrome. Conditioning chemotherapy (FluBu) and preconditioning ALC were significant risk factors for the development of IMC. (B) Box and whisker plot comparing day 0 ALC of patients conditioned with busulfan and cyclophosphamide (BuCy) and FluBu (P = .001). (C) Box and whisker plot comparing preconditioning ALC of patients with and without an episode of IMC (P = .003). GvHD, graft-versus-host disease. David Deambrosis et al. Blood Adv 2019;3: © 2019 by The American Society of Hematology


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