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Opening of the Clamp Cell

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Presentation on theme: "Opening of the Clamp Cell"— Presentation transcript:

1 Opening of the Clamp Cell
Viola Ellison, Bruce Stillman  Cell  Volume 106, Issue 6, Pages (September 2001) DOI: /S (01)

2 Figure 1 Comparison of Three Clamps: E. coli β Subunit, Phage T4 gp45, and Human PCNA Cell  , DOI: ( /S (01) )

3 Figure 2 A Generic AAA+ Protein
The domains of a AAA+ protein are shown, as is the β interacting element (BIE) that is present in the δ subunit off the E. coli clamp loader. Figure drawn by J. Duffy (Cold Spring Harbor Laboratory) Cell  , DOI: ( /S (01) )

4 Figure 3 A δ Fragment and the β Subunit
Figure drawn by J. Duffy (Cold Spring Harbor Laboratory) Cell  , DOI: ( /S (01) )

5 Figure 4 Clamp Loading Figure drawn by J. Duffy (Cold Spring Harbor Laboratory) Cell  , DOI: ( /S (01) )

6 Figure 5 Model of the Phage T4 Polymerase and its Clamp (Alley et al., 2001; Shamoo and Steitz, 1999) Figure from Alley et al. (2001) Cell  , DOI: ( /S (01) )


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