Presentation is loading. Please wait.

Presentation is loading. Please wait.

An introduction to infectious diseases epidemiology

Published byUtami Agusalim Modified over 5 years ago

Similar presentations

Presentation on theme: "An introduction to infectious diseases epidemiology"— Presentation transcript:

1 An introduction to infectious diseases epidemiology
Jon Otter, PhD FRCPath Imperial College London @jonotter Blog: Slides:

2

3

4

5 Infectious diseases are caused by pathogenic microorganisms, such as bacteria, viruses, parasites or fungi; the diseases can be spread, directly or indirectly, from one person to another (World Health Organisation)

6 Healthcare-associated infections (HCAIs) Tropical diseases
MRSA C. difficile CPE Tropical diseases Zika Dengue Worms Vaccine-preventable Smallpox Measles Mumps Sexually transmitted infections (STIs) Chlamydia Gonorrhoea HPV HIV

7 Vaccines Antibiotics & HCAI* Crapsules Applied research
Disease Detectives ID** epi needs you * HCAI = Healthcare-associated infection. ** ID = infectious diseases.

8 Vaccines Antibiotics & HCAI* Crapsules Applied research
Disease Detectives ID** epi needs you * HCAI = Healthcare-associated infection. ** ID = infectious diseases.

9

10

11

12 Vaccines Antibiotics & HCAI* Crapsules Applied research
Disease Detectives ID** epi needs you * HCAI = Healthcare-associated infection. ** ID = infectious diseases.

13

14 MRSA infection

15 Vaccines Antibiotics & HCAI* Crapsules Applied research
Disease Detectives ID** epi needs you * HCAI = Healthcare-associated infection. ** ID = infectious diseases.

16 Clostridium difficile infection
Recurrence rate 15-35%

17 Faecal microbiota transplant for recurrent CDI
Patients with recurrent CDI randomised to FMT (n=16), vancomycin (n=12) or vancomycin + bowel lavage (n=13) van Nood et al. N Engl J Med 2013;368:

18

19 Recurrent CDI is just the start…
Disease group Diseases Intestinal Recurrent CDI, Chron’s disease, ulcerative colitis, IBS, dislodging antibiotic resistant bacteria Metabolic Metabolic syndrome, obesity, Type 2 diabetes, cardiovascular diseases, non-alcoholic liver diseases Neuropsychiatric Parkinson’s, MS, myoclonus dystonia, autism, chronic fatigue syndrome Autoimmune Arthritis, various other Allergic Atopy, asthma, various cancers Xu et al. World J Gasteroenterol 2015;21:

20 Vaccines Antibiotics & HCAI* Crapsules Applied research
Disease Detectives ID** epi needs you * HCAI = Healthcare-associated infection. ** ID = infectious diseases.

21 CPE outbreak; total number of cases
8 cases first identified by clinical culture, 32 by screening culture; of these 32, 14 had a subsequent positive clinical culture Otter et al. Sci Rep 2017;7:12711.

22 Cost of an outbreak - results
Economic evaluation of a 40 case outbreak of CPE. Error bars represent range Otter et al. Clin Microbiol Infect 2017;23:

23 Vaccines Antibiotics & HCAI* Crapsules Applied research
Disease Detectives ID** epi needs you * HCAI = Healthcare-associated infection. ** ID = infectious diseases.

24

25 Vaccines Antibiotics & HCAI* Crapsules Applied research
Disease Detectives ID** epi needs you * HCAI = Healthcare-associated infection. ** ID = infectious diseases.

26 Clinical Academic Other Routes into infectious disease epidemiology
Medicine, Nursing, Pharmacy, Clinical Scientist Academic Microbiology, Maths, Public Health, IT/Data Science Other Laboratory science, chemistry

27 Resources Link Description BBC Bitesize
Seeing the unseen bacteria on hands CDC Zombie Preparedness Educational epi games and resources CDC Epidemic Intelligence Service Where “Disease Detectives” are made in America e-Bug Educational resources for HCAI and AMR aimed at school children ECDC Disease Atlas European data on HCAI indicators and AMR ICL HCAI & AMR school resources Resources for school activities from Imperial College London Institute of Biomedical Sciences The professional body for biomedical scientists and support staff. PHE AMR Fingertips portal English data on HCAI indicators PHE infectious diseases index Alphabetical index of infectious diseases PHE Field Epidemiology Service Where “Disease Detectives” are make in the UK Reflections on IPC blog Weekly (ish) blog on applied HCAI and AMR epidemiology Vomiting Larry This ‘friendly’ mannequin shows us what happens when we puke… WHO infectious diseases pages Information about infectious diseases from the WHO

28 An introduction to infectious diseases epidemiology
Jon Otter, PhD FRCPath Imperial College London @jonotter Blog: Slides:

Download ppt "An introduction to infectious diseases epidemiology"

Similar presentations

Environmental Hazards and Human Health

Environmental Hazards and Human Health
 A public health science (foundation of public health)  Impacts personal decisions about our lifestyles  Affects government, public health agency and.

 A public health science (foundation of public health)  Impacts personal decisions about our lifestyles  Affects government, public health agency and.
1 Institute of Epidemiology and Infectious Diseases Research Activities The L.V. Gromashevsky Institute of Epidemiology and Infectious Diseases Svetlana.

1 Institute of Epidemiology and Infectious Diseases Research Activities The L.V. Gromashevsky Institute of Epidemiology and Infectious Diseases Svetlana.
Leav, B. A., et al.(2010) “Serum Anti-toxin B Antibody Correlates with Protection from Recurrent Clostridium Difficile Infection (CDI)”. Vaccine 28: 965-69.

Leav, B. A., et al.(2010) “Serum Anti-toxin B Antibody Correlates with Protection from Recurrent Clostridium Difficile Infection (CDI)”. Vaccine 28:
Patient Care In Medical Imaging RAD 233 Abdulrahman Al Sayyari, PhD, MBA, &MS.c.

Patient Care In Medical Imaging RAD 233 Abdulrahman Al Sayyari, PhD, MBA, &MS.c.
Infection Control and the Bugs. Blanche Lenard RN, CIC Education Session Infection Control in Healthcare  Environmental Cleaning  Routes of Transmission.

Infection Control and the Bugs. Blanche Lenard RN, CIC Education Session Infection Control in Healthcare  Environmental Cleaning  Routes of Transmission.
9/22/20151 ACCESS Human Biology. Disease Causing Micro organisms. Vera Harding.

9/22/20151 ACCESS Human Biology. Disease Causing Micro organisms. Vera Harding.
SPM 100 Clinical Skills Lab 1 Standard Precautions Sterile Technique Daryl P. Lofaso, M.Ed, RRT.

SPM 100 Clinical Skills Lab 1 Standard Precautions Sterile Technique Daryl P. Lofaso, M.Ed, RRT.
What is the Deal About FMT? Herbert L. DuPont, MD Director, Center for Infectious Diseases, University of Texas School of Public Health President, Kelsey.

What is the Deal About FMT? Herbert L. DuPont, MD Director, Center for Infectious Diseases, University of Texas School of Public Health President, Kelsey.
Diseases Learning Targets and Success Criteria. Infection Learning Target I can explain how viruses, bacteria, fungi and parasites may infect the human.

Diseases Learning Targets and Success Criteria. Infection Learning Target I can explain how viruses, bacteria, fungi and parasites may infect the human.
Moving forward together infection prevention and control and AMR Rose Gallagher Nurse Advisor Infection Prevention and Control Royal College of Nursing.

Moving forward together infection prevention and control and AMR Rose Gallagher Nurse Advisor Infection Prevention and Control Royal College of Nursing.
SPM 100 Skills Lab 1 Standard Precautions Sterile Technique Daryl P. Lofaso, M.Ed, RRT Clinical Skills Lab Coordinator.

SPM 100 Skills Lab 1 Standard Precautions Sterile Technique Daryl P. Lofaso, M.Ed, RRT Clinical Skills Lab Coordinator.
30mm 10mm logo safe area 10mm logo safe area EDITING NOTES All copy must stay within the content limit guidelines. Any image added to a slide with text.

30mm 10mm logo safe area 10mm logo safe area EDITING NOTES All copy must stay within the content limit guidelines. Any image added to a slide with text.
Specialties and your career. Starting work in a lab When you apply for your first job in a laboratory it will be in a specific discipline: haematology.

Specialties and your career. Starting work in a lab When you apply for your first job in a laboratory it will be in a specific discipline: haematology.
Healthcare Scientists Biomedical Scientists. Science in the service of life A career in Biomedical Science.

Healthcare Scientists Biomedical Scientists. Science in the service of life A career in Biomedical Science.
Public Health Training at Imperial College Christopher Millett Senior Lecturer / Educational Supervisor School of Public Health.

Public Health Training at Imperial College Christopher Millett Senior Lecturer / Educational Supervisor School of Public Health.
The PHE Field Epidemiology Service Dr Paul Crook Consultant Epidemiologist Field Epidemiology Services, Victoria Serving Kent, Surrey & Sussex, London,

The PHE Field Epidemiology Service Dr Paul Crook Consultant Epidemiologist Field Epidemiology Services, Victoria Serving Kent, Surrey & Sussex, London,
Using AMR surveillance for developing policy AMR meeting Washington 13 April 2016.

Using AMR surveillance for developing policy AMR meeting Washington 13 April 2016.
Selling your work to colleagues and society: how to use social media Jon Otter, PhD FRCPath Imperial College Healthcare NHS Trust 

Selling your work to colleagues and society: how to use social media Jon Otter, PhD FRCPath Imperial College Healthcare NHS Trust 
NEW TECHNOLOGIES IN VACCINES. Vaccination – is the introduction into the body of a weakened, killed or piece of a disease-causing agent to prevent disease.

NEW TECHNOLOGIES IN VACCINES. Vaccination – is the introduction into the body of a weakened, killed or piece of a disease-causing agent to prevent disease.

Similar presentations

Ads by Google