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Published byLinda Griffin Modified over 5 years ago
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Protection from 4T1 tumor rechallenge in treated mice.
Protection from 4T1 tumor rechallenge in treated mice. A, Tumor resected mice that survived to day 120 after treatment with α-GalCer–loaded DCs, gemcitabine (GEM), GEM plus α-GalCer–loaded DCs, or cyclophosphamide (CPX) plus α-GalCer–loaded DCs were rechallenged in the contralateral mammary fat pad with 4T1 cells. Tumor volume was compared with tumors grown in naïve mice (n = 5–8/group over two independent experiments). B, Metastatic burden was measured by clonogenic assay at day 25 after 4T1 inoculation (n = 5–8/group over two independent experiments). *, P < 0.05 compared with naïve challenge. Simon Gebremeskel et al. Cancer Immunol Res 2017;5: ©2017 by American Association for Cancer Research
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