1. Improvements in Bladder Diary Variables
Urgency episodes per 24 h
Severe
Urgency episodes
per 24 h
Micturitions per 24 h * † ‡
Statistical analysis for treatment differences using analysis of covariance.
*P<0.05; †P<0.01; ‡P<0.001.
PBO + α-blocker, 17%; TER+ α-blocker, 14%
Adapted from Herschorn S. AUA 2008.

2. Improvements in IPSS * Total index Storage subscale Voiding subscale
Statistical analysis for treatment differences using analysis of covariance.
*P<
Adapted from Herschorn S. AUA 2008.

3. Change in Post-void Residual Urine
Parameter
Tolterodine ER (n=35)
Solifenacin (n=36)
Darifenacin (n=36)
Mean at baseline
32.7
36.5
31.5
Mean at week 12
36.2
39.8
48.7
Mean change to week 12
3.5
3.3
17.2*
Percentage change to week 12
10.7
9.0
54.6*
*Two-sided P value for paired t test on change from baseline.
Adapted from Kaplan SA. AUA 2008.