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Predominant localization of the major Alternaria allergen Alt a 1 in the cell wall of airborne spores  Teresa E. Twaroch, MSc, Elsa Arcalís, PhD, Katja.

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Presentation on theme: "Predominant localization of the major Alternaria allergen Alt a 1 in the cell wall of airborne spores  Teresa E. Twaroch, MSc, Elsa Arcalís, PhD, Katja."— Presentation transcript:

1 Predominant localization of the major Alternaria allergen Alt a 1 in the cell wall of airborne spores  Teresa E. Twaroch, MSc, Elsa Arcalís, PhD, Katja Sterflinger, PhD, Eva Stöger, PhD, Ines Swoboda, PhD, Rudolf Valenta, MD  Journal of Allergy and Clinical Immunology  Volume 129, Issue 4, Pages (April 2012) DOI: /j.jaci Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Localization of Alt a 1 and Alt a 8 by immunogold electron microscopy. A, Specific labeling of Alt a 1 in the melanin layer of Alternaria spores. B and C, Ultrathin section of hyphae of Alternaria alternata after staining with anti-Alt a 8 antibodies. C, Enlargement of the inset in B. Electron-dense material in vacuolar-like compartments is marked by asterisks. cw, Cell wall; m, mitochondria; ml, melanin layer. Scale bars = 0.5 μm. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions


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