1. Average percent change in serum leptin and soluble leptin receptor (sOB-R) levels in response to rhLeptin administration at a low dose (0.01 mg/kg) (n = 5 subjects).
Average percent change in serum leptin and soluble leptin receptor (sOB-R) levels in response to rhLeptin administration at a low dose (0.01 mg/kg) (n = 5 subjects). Arrow indicates rhLeptin administration. Values are expressed as means ± SE. *P < 0.01, #P < 0.05 vs. baseline level before rhLeptin dose.
Jean L. Chan et al. Diabetes 2002;51:
©2002 by American Diabetes Association