1. A New Path through the Nuclear Pore
Alejandro Gozalo, Maya Capelson 
Cell 
Volume 167, Issue 5, Pages (November 2016)
DOI: /j.cell
Copyright © 2016 Elsevier Inc. Terms and Conditions

2. Figure 1
Previous and Revised Models of the NPC and Their Implications for Mechanisms of mRNA Export
The newly obtained structure of the Nup82-Nup84 cytoplasmic complex assembly demonstrates that the previously proposed extended cytoplasmic filaments, formed by the Nup82 complex, are in fact more like struts oriented inward toward the NPC transport channel. The Nup82 complex FG domains, which interact with transport receptors, are thus positioned in close proximity to the FG domains of the transport channel, forming an “FG continuum.” This model reveals a streamlined mRNA export process, with an easy route for the traveling mRNP particles from the inner transport channel to the remodeling proteins bound by the Nup82 “struts.”
Cell  , DOI: ( /j.cell )
Copyright © 2016 Elsevier Inc. Terms and Conditions