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Excess Cancer Mortality in Six Dutch Pedigrees with the Familial Atypical Multiple Mole- Melanoma Syndrome from 1830 to 1994  Elysée T.M. Hille, Erik van.

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Presentation on theme: "Excess Cancer Mortality in Six Dutch Pedigrees with the Familial Atypical Multiple Mole- Melanoma Syndrome from 1830 to 1994  Elysée T.M. Hille, Erik van."— Presentation transcript:

1 Excess Cancer Mortality in Six Dutch Pedigrees with the Familial Atypical Multiple Mole- Melanoma Syndrome from 1830 to 1994  Elysée T.M. Hille, Erik van Duijn, Nelleke A. Gruis, Frits R. Rosendaal, Wilma Bergman  Journal of Investigative Dermatology  Volume 110, Issue 5, Pages (May 1998) DOI: /j x Copyright © 1998 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 Excess mortality is present in most families. SMR with 95%CI, per FAMMM family from 1850 till 1994, ≥ 20 y of age. Journal of Investigative Dermatology  , DOI: ( /j x) Copyright © 1998 The Society for Investigative Dermatology, Inc Terms and Conditions

3 Figure 2 The SMR is rising over calendar time. SMR with 95% CI, in FAMMM families according to calendar periods, ≥ 20 y of age. Journal of Investigative Dermatology  , DOI: ( /j x) Copyright © 1998 The Society for Investigative Dermatology, Inc Terms and Conditions

4 Figure 3 Excess mortality is confined to age groups 40–70 y. SMR with 95%CI, in FAMMM families according to age groups from 1850 till 1994. Journal of Investigative Dermatology  , DOI: ( /j x) Copyright © 1998 The Society for Investigative Dermatology, Inc Terms and Conditions


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