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Fraser D. Rubens, MD, MS, Gilbert Lavalee, Marc A

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Presentation on theme: "Fraser D. Rubens, MD, MS, Gilbert Lavalee, Marc A"— Presentation transcript:

1 Delayed Thrombin Generation With Hirudin Anticoagulation During Prolonged Cardiopulmonary Bypass 
Fraser D. Rubens, MD, MS, Gilbert Lavalee, Marc A. Ruel, MD, MPH, Thierry Mesana, MD, PhD, Michael Bourke, MD  The Annals of Thoracic Surgery  Volume 79, Issue 1, Pages (January 2005) DOI: /S (03)

2 Fig 1 Effect of recombinant hirudin (lepirudin) on measured hirudin levels, as well as thrombin generation and activity during a case of prolonged cardiopulmonary bypass (CPB). Diamonds = hirudin (μg/mL); squares = TAT (μg/L); triangles = F1.2 (nmol/L). (TAT = thrombin antithrombin III; F1.2 = prothrombin fragment 1.2.) The Annals of Thoracic Surgery  , DOI: ( /S (03) )

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