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Complications and outcomes (A) and the number of complications and outcomes (B) for 86 cases of severe knowlesi malaria. Complications and outcomes (A) and the number of complications and outcomes (B) for 86 cases of severe knowlesi malaria. ARDS, hypoxia with a respiratory rate of >30, presence of pulmonary infiltrates, or requiring ventilation; acute kidney injury, creatinine levels of >265 μmol/liter (3 mg/dl) or requiring dialysis; hypotension, systolic blood pressure of <80 mm Hg or started on ionotropes; jaundice, total bilirubin level of ≥43 μmol/liter (3 mg/dl); acidosis, lactate level of >6 mmol/liter; hypoglycemia, glucose level of <2.2 mmol/liter (40 mg/dl). (Data obtained from references 28, 32 – 35, 43, 45, and 127.) Balbir Singh, and Cyrus Daneshvar Clin. Microbiol. Rev. 2013; doi: /CMR
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