1. BSAS Annual Conference, Belfast, 12-14th April, 2010
Effect of sodium selenite on male Sprague - Dawley rats exposed to sublethal dose of cadmium chloride
F Jabeen, A S Chaudhry
School of Agriculture Food and Rural Development,
Newcastle University, UK

2. BSAS Annual Conference, Belfast, 12-14th April, 2010
Objective
To assess the protective role of selenium against cadmium induced toxicity in rats

3. RESULTS Cadmium (Cd) = occupational and environmental toxin
Selenium (Se) = important antioxidant
RESULTS
Body weights were lower for Cd,
higher for Se and comparable for
Cd -Se groups with control
The mean liver and kidney weights
and Hb were significantly lower
in the Cd than other groups
Hb in Se group was significantly
higher than other groups
Cd was many fold higher in kidneys and livers for the Cd than the control group
Cd was below the detection limit
in Se but it was many folds higher for the Cd-Se than the control group and lower than the Cd group
High levels of Se were detected in Cd than the Cd-Se group

4. Conclusion
This study indicates that Selenium may have a protective effect against cadmium induced toxicity