Presentation is loading. Please wait.

Presentation is loading. Please wait.

Differential effects of insulin-like growth factor-I and gonadotropins on the proliferative activity of two subgroups of granulosa cells: cumulus oophorus.

Published byMarvin Carroll Modified over 5 years ago

Similar presentations

Presentation on theme: "Differential effects of insulin-like growth factor-I and gonadotropins on the proliferative activity of two subgroups of granulosa cells: cumulus oophorus."— Presentation transcript:

1 Differential effects of insulin-like growth factor-I and gonadotropins on the proliferative activity of two subgroups of granulosa cells: cumulus oophorus and mural granulosa cells  Firouz Khamsi, Silvie Roberge, Ph.D.  Fertility and Sterility  Volume 75, Issue 5, Pages (May 2001) DOI: /S (01)

2 Figure 1 Diagram showing the design of Experiment 1. The experiment was done twice, using 10 rats per in vivo treatment each time. Khamsi. Effects of IGFI and gonadotropins on granulosa cells. Fertil Steril 2001. Fertility and Sterility  , DOI: ( /S (01) )

3 Figure 2 Effect of IGFI in vitro and eCG in vivo on 3H-thymidine incorporation during the 28-hour culture of mural granulosa cells (MGC) and oocyte-cumulus complexes (CC) of immature rats. The data are mean values (± SEM) for pooled data from two experiments, with six in vitro replicates per IGFI concentration. Circles with unbroken line indicate CC from saline-treated animals. Triangles with unbroken line indicates MGC from eCG-treated animals. Stars with unbroken line indicate MGC from animals treated with saline. Asterisks indicate values significantly different from control (no IGFI) within the same cell type and in vivo treatment (P<.05). Khamsi. Effects of IGFI and gonadotropins on granulosa cells. Fertil Steril 2001. Fertility and Sterility  , DOI: ( /S (01) )

4 Figure 3 Thymidine incorporation of oocyte–cumulus complexes from rats treated in vivo with either LR3-IGFI (lined bars) or saline (open bars). Cultured cumulus cells (CC) were treated in vitro with FSH, LH, or saline (control). Khamsi. Effects of IGFI and gonadotropins on granulosa cells. Fertil Steril 2001. Fertility and Sterility  , DOI: ( /S (01) )

5 Figure 4 Thymidine incorporation of mural granulosa cells (MGC) from rats treated in vivo with either LR3-IGFI (lined bars) or saline (open bars). Cultured mural granulosa cells (MGC) were treated in vitro with FSH, LH, or saline (control). Khamsi. Effects of IGFI and gonadotropins on granulosa cells. Fertil Steril 2001. Fertility and Sterility  , DOI: ( /S (01) )

Download ppt "Differential effects of insulin-like growth factor-I and gonadotropins on the proliferative activity of two subgroups of granulosa cells: cumulus oophorus."

Similar presentations

MTOR kinase inhibition results in oocyte loss characterized by empty follicles in human ovarian cortical strips cultured in vitro  Marie McLaughlin, Ph.D.,

MTOR kinase inhibition results in oocyte loss characterized by empty follicles in human ovarian cortical strips cultured in vitro  Marie McLaughlin, Ph.D.,
Glutathione S-transferase theta 1 expressed in granulosa cells as a biomarker for oocyte quality in age-related infertility  Megumu Ito, M.D., Miho Muraki,

Glutathione S-transferase theta 1 expressed in granulosa cells as a biomarker for oocyte quality in age-related infertility  Megumu Ito, M.D., Miho Muraki,
Heat-killed Lactobacillus plantarum L-137 suppresses naturally fed antigen–specific IgE production by stimulation of IL-12 production in mice  Shinji.

Heat-killed Lactobacillus plantarum L-137 suppresses naturally fed antigen–specific IgE production by stimulation of IL-12 production in mice  Shinji.
Jong Yeob Choi, Ph. D. , Min Wha Jo, M. S. , Eun Young Lee, M. S

Jong Yeob Choi, Ph. D. , Min Wha Jo, M. S. , Eun Young Lee, M. S
Developmental programming: prenatal testosterone excess disrupts anti-Müllerian hormone expression in preantral and antral follicles  Almudena Veiga-Lopez,

Developmental programming: prenatal testosterone excess disrupts anti-Müllerian hormone expression in preantral and antral follicles  Almudena Veiga-Lopez,
In vitro maturation, fertilization, and development of human germinal vesicle oocytes collected from stimulated cycles  Byung-Ki Kim, Ph.D., Sang-Chan.

In vitro maturation, fertilization, and development of human germinal vesicle oocytes collected from stimulated cycles  Byung-Ki Kim, Ph.D., Sang-Chan.
Leukemia inhibitory factor induces cumulus expansion in immature human and mouse oocytes and improves mouse two-cell rate and delivery rates when it is.

Leukemia inhibitory factor induces cumulus expansion in immature human and mouse oocytes and improves mouse two-cell rate and delivery rates when it is.
Coculture with cumulus cells improves maturation of mouse oocytes denuded of the cumulus oophorus: observations of nuclear and cytoplasmic events  Li.

Coculture with cumulus cells improves maturation of mouse oocytes denuded of the cumulus oophorus: observations of nuclear and cytoplasmic events  Li.
Adiponectin increases insulin-like growth factor I-induced progesterone and estradiol secretion in human granulosa cells  Christine Chabrolle, M.D., Lucie.

Adiponectin increases insulin-like growth factor I-induced progesterone and estradiol secretion in human granulosa cells  Christine Chabrolle, M.D., Lucie.
Lapatinib inhibits meiotic maturation of porcine oocyte-cumulus complexes cultured in vitro in gonadotropin-supplemented medium  Eva Nagyova, D.V.M.,

Lapatinib inhibits meiotic maturation of porcine oocyte-cumulus complexes cultured in vitro in gonadotropin-supplemented medium  Eva Nagyova, D.V.M.,
Acquisition and loss of oocyte meiotic and developmental competence during in vitro antral follicle growth in mouse  Ingrid Segers, M.Sc., Tom Adriaenssens,

Acquisition and loss of oocyte meiotic and developmental competence during in vitro antral follicle growth in mouse  Ingrid Segers, M.Sc., Tom Adriaenssens,
Cigarette smoke condensate exposure delays follicular development and function in a stage-dependent manner  Jean Clair Sadeu, M.D., Ph.D., Warren G. Foster,

Cigarette smoke condensate exposure delays follicular development and function in a stage-dependent manner  Jean Clair Sadeu, M.D., Ph.D., Warren G. Foster,
Keri Greenseid, M. D. , Sangita Jindal, Ph. D. , Athena Zapantis, B. S

Keri Greenseid, M. D. , Sangita Jindal, Ph. D. , Athena Zapantis, B. S
The apoptotic profile of human cumulus cells changes with patient age and after exposure to sperm but not in relation to oocyte maturity  Odette Moffatt,

The apoptotic profile of human cumulus cells changes with patient age and after exposure to sperm but not in relation to oocyte maturity  Odette Moffatt,
162. Stability of Polymer/Plasmid DNA Complexes In Vitro and In Vivo

162. Stability of Polymer/Plasmid DNA Complexes In Vitro and In Vivo
MRNA expression pattern of insulin-like growth factor components of granulosa cells and cumulus cells in women with and without polycystic ovary syndrome.

MRNA expression pattern of insulin-like growth factor components of granulosa cells and cumulus cells in women with and without polycystic ovary syndrome.
Androstenedione induces abnormalities in morphology and function of developing oocytes, which impairs oocyte meiotic competence  Wataru Tarumi, M.Sc.,

Androstenedione induces abnormalities in morphology and function of developing oocytes, which impairs oocyte meiotic competence  Wataru Tarumi, M.Sc.,
Hung-Ching Liu, Ph.D., Zhiying He, M.S., Zev Rosenwaks, M.D. 

Hung-Ching Liu, Ph.D., Zhiying He, M.S., Zev Rosenwaks, M.D. 
The antifibrotic drug halofuginone inhibits proliferation and collagen production by human leiomyoma and myometrial smooth muscle cells  Meagan M. Grudzien,

The antifibrotic drug halofuginone inhibits proliferation and collagen production by human leiomyoma and myometrial smooth muscle cells  Meagan M. Grudzien,
Expression of growth differentiation factor-9 and bone morphogenetic protein-15 in oocytes and cumulus granulosa cells of patients with polycystic ovary.

Expression of growth differentiation factor-9 and bone morphogenetic protein-15 in oocytes and cumulus granulosa cells of patients with polycystic ovary.

Similar presentations

Ads by Google