3. The Need for Serial Troponin Testing
absolute cTn elevations are seen in multiple chronic cardiac and noncardiac conditions
rise or fall !! in serial cTn levels strongly supports an acutely evolving cardiac injury (most commonly, acute myocardial infarction)

5. Case #1
a 48-year-old man who presented to the emergency department with chest discomfort lasting 2 hours and a 3-day history of flu-like symptoms whose ECG showed diffuse ST-segment changes
flu-like
2 hours
ST-changes

6. Case #2
a 60-year-old woman with a medical history of heart failure who presented to the emergency department with chest pain lasting 1.5 hours whose ECG was nondiagnostic
heart failure
1.5 hours
ECG nondiagnostic

7. Case #3
a 54-year-old man with a medical history of diabetes mellitus who presented with chest discomfort lasting 1 hour whose ECG was normal
diabetes mellitus
1 hour
ECG normal

8. Case #1
0.9
The cutoff for the TnI assay (0.04 ng/mL)

9. Case #2
0.09
The cutoff for the TnI assay (0.04 ng/mL)
0.05

10. Case #3 53
6.3
0.06
The cutoff for the TnI assay (0.04 ng/mL)