1. Effect of circadian forced desynchrony on behavioral manifestations of depression.
Effect of circadian forced desynchrony on behavioral manifestations of depression. A, Fraction of 0.1% saccharin consumption averaged over 8 d for LD24 control, LD22 aligned, and LD22 misaligned rats. Boxes outline the lower (25%) and upper (75%) quartiles, and the line denotes the median. Error bars represent the 95% confidence intervals. Different letters denote statistically significant differences (p < 0.05). B, Fraction of time spent in the perimeters of the open field test arena, during the light and dark phases in the same groups. C, Immobility time during the 5-min FST in the light and dark phases. Different letters denote statistically significant differences (p < 0.05). All values represent mean ± SE.
Miriam Ben-Hamo et al. eNeuro 2016;3:ENEURO
©2016 by Society for Neuroscience