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The common cold: Effects of intranasal fluticasone propionate treatment
Tuomo Puhakka, MDa, Mika J. Mäkelä, MD a,b, Kristiina Malmström, MDa, Matti Uhari, MDc, Johannes Savolainen, MDa,b, Erkki O. Terho, MDb, Markku Pulkkinen, RNd, Olli Ruuskanen, MDa Journal of Allergy and Clinical Immunology Volume 101, Issue 6, Pages (June 1998) DOI: /S (98)70301-X Copyright © 1998 Mosby, Inc. Terms and Conditions
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Fig. 1 Frequency of respiratory symptoms by day ( n = 199). Dashed line, FP; solid line, placebo. Journal of Allergy and Clinical Immunology , DOI: ( /S (98)70301-X) Copyright © 1998 Mosby, Inc. Terms and Conditions
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Fig. 2 Resolution of respiratory symptoms (n = 199). Subjects were asked to score their symptoms from 0 to 3, with 0 referring to absence of symptoms. Rhinorrhea score was obtained by summing symptom scores of watery rhinitis and purulent rhinitis (scale of severity, 0 to 6). *Significance difference (p < 0.05, as determined by Wilcoxon test). Dashed line, FP; solid line, placebo. Journal of Allergy and Clinical Immunology , DOI: ( /S (98)70301-X) Copyright © 1998 Mosby, Inc. Terms and Conditions
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Fig. 3 Resolution of respiratory symptoms in culture-positive (dashed lines) and culture-negative (solid lines) subjects for S. pneumoniae, H. influenzae, or M. catarrhalis in the nasopharynx on day 1. Symptom score was obtained by summing the symptom scores of purulent rhinitis, sore throat, cough, and sputum (scale of severity, 0 to 12). *Significance difference (p < 0.05, as determined by the Wilcoxon test). Journal of Allergy and Clinical Immunology , DOI: ( /S (98)70301-X) Copyright © 1998 Mosby, Inc. Terms and Conditions
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