1. Lymphocytic hypophysitis.
Lymphocytic hypophysitis. A 30-year-old woman presented with headache and visual loss and endocrine assessment confirmed panhypopituitarism. T1W sagittal (A) and coronal (B), T2W coronal (C and D) and gadolinium-enhanced T1W (E) MRIs show an enhancing bulky pituitary gland, absent posterior pituitary high signal (indicating central diabetes insipidus), thickening of the infundibulum and an enhancing optic chiasm/hypothalamic mass. There is oedema in the hypothalamus, which is tracking along the optic nerves. There is enhancement of the thickened dura as it passes posteriorly along the clivus. Six weeks later, after a course of corticosteroids, there is a dramatic improvement with only a small amount of residual enhancing tissue (F, T1W gadolinium-enhanced sagittal MRI).
Shelley Renowden Pract Neurol 2015;15:26-41
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