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Neoglycopeptides as Inhibitors of Oligosaccharyl Transferase

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Presentation on theme: "Neoglycopeptides as Inhibitors of Oligosaccharyl Transferase"— Presentation transcript:

1 Neoglycopeptides as Inhibitors of Oligosaccharyl Transferase
Stéphane Peluso, Maria de L. Ufret, Mary K. O'Reilly, Barbara Imperiali  Chemistry & Biology  Volume 9, Issue 12, Pages (December 2002) DOI: /S (02)

2 Figure 1 Peptides and Glycopeptide Conjugates Presented in This Study
Chemistry & Biology 2002 9, DOI: ( /S (02) )

3 Figure 2 Conformational Preferences
Conformational preferences of (A) glycosyl amide, (B) glycosyl hydrazide, (C) glycosyl oxime, and (D) glycosylamine. Chemistry & Biology 2002 9, DOI: ( /S (02) )

4 Figure 3 Proposal for the Role of Isomerization in Promoting Product Release Chemistry & Biology 2002 9, DOI: ( /S (02) )


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