1. Acute circulatory actions of intravenous amiodarone loading in cardiac surgical patients 
Albert T Cheung, MD, Stuart J Weiss, MD, PhD, Joseph S Savino, MD, Warren J Levy, MD, John G Augoustides, MD, Amy Harrington, Timothy J Gardner, MD 
The Annals of Thoracic Surgery 
Volume 76, Issue 2, Pages (August 2003)
DOI: /S (03)

2. Fig 1
Systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP) after study drug administration (mean ± SEM). Analysis of variance for repeated measures demonstrated a significant time and group interaction on the changes in SBP (p < 0.005), DBP (p < 0.003), and MAP (p < 0.004) over time in the first 15 minutes after drug administration. The group effect was not significant beyond 15 minutes after drug administration. (Solid circles and triangles = group A, amiodarone; open circles and triangles = group B, control.)
The Annals of Thoracic Surgery  , DOI: ( /S (03) )

3. Fig 2
Heart rate, pulmonary artery systolic pressure (PAS), pulmonary artery diastolic pressure (PAD), and central venous pressure (CVP) after study drug administration (mean ± SEM). Analysis of variance for repeated measures demonstrated a significant group effect on the changes in heart rate (p = 0.024) over the entire period of study after drug administration. There was no significant group effect on the changes in PAS (p = 0.18), PAD (p = 0.08), and CVP (p = 0.87) over the period of study. (Solid circles and triangles = group A, amiodarone; open circles and triangles = group B, control.)
The Annals of Thoracic Surgery  , DOI: ( /S (03) )

4. Fig 3
Cardiac output (CO) and mixed venous oxygen saturation (SVO) after study drug administration (mean ± SEM). Analysis of variance for repeated measures detected a significant group effect on the changes in CO (p = 0.03). There was no significant group effect on the changes in SVO (p = 0.20) over the period of study. (Solid circles = group A, amiodarone; open circles = group B, control.)
The Annals of Thoracic Surgery  , DOI: ( /S (03) )

5. Fig 4
Left ventricular fractional area change (FAC) and end-systolic meridional wall stress (ESWS) were measured using the transesophageal echocardiography transgastric left ventricular short-axis view at 5-minute intervals after study drug administration (mean ± SEM). There was no significant group or time effect on the changes in FAC (p = 0.34) and ESWS (p = 0.47). (Solid circles = group A, amiodarone; open circles = group B, control.)
The Annals of Thoracic Surgery  , DOI: ( /S (03) )

6. Fig 5
Left ventricular end-diastolic area (EDA) and end-systolic area (ESA) were measured using the transesophageal echocardiography transgastric left ventricular short-axis view at 5-minute intervals after study drug administration (mean ± SEM). There was a significant group effect on the changes in EDA (p = 0.01). The ESA was greater after drug administration in the amiodarone group, but the group effect was not quite significant (p = 0.08). (Solid circles = group A, amiodarone; open circles = group B, control.) (LVSAX = left ventricular short-axis.)
The Annals of Thoracic Surgery  , DOI: ( /S (03) )