1. Spontaneous EPSC and IPSC dynamics in 3 mm and 1 mm Ca2+.
Spontaneous EPSC and IPSC dynamics in 3 mm and 1 mm Ca2+. A1, Spontaneous synaptic potentials were recorded from identified CA3 pyramidal cells at different membrane holding levels to detect excitatory (EPSCs) and inhibitory (IPSCs) components in 3 mm (n = 6 cells) and 1 mm (n = 6 cells) Ca2+. B1, Cumulative distribution of the interevent interval of spontaneous EPSCs (left) and spontaneous IPSCs (right) recorded at −60 mV in the two different Ca2+ concentrations. C1, Group data of mean frequency for spontaneous EPSCs (left) and IPSCs (right) as detected at −60 mV with standard pipette solutions (see Materials and Methods) and at different potentials with QX314. D1, Group data of mean amplitude for spontaneous EPSCs (left) and IPSCs (right). E1, Group data of total charge for spontaneous EPSCs (left) and IPSCs (right). A2, Spontaneous synaptic potentials recorded in identified interneurons in 3 mm (n = 6) and 1 mm (n = 4) Ca2+. B2, Cumulative distribution of the interevent interval of spontaneous EPSCs (left) and IPSCs (right) recorded from interneurons at the two different Ca2+ concentrations. C2, Group data of mean frequency for spontaneous EPSCs (left) and IPSCs (right). D2, Group data of mean amplitude for spontaneous EPSCs (left) and IPSCs (right). *p < 0.05; **p < E2, Group data of total charge for spontaneous EPSCs (left) and IPSCs (right).
Paloma Aivar et al. J. Neurosci. 2014;34:
©2014 by Society for Neuroscience