Presentation is loading. Please wait.

Presentation is loading. Please wait.

A methacholine challenge dose-response study for development of a pharmacodynamic bioequivalence methodology for albuterol metered-dose inhalers  Peter.

Published byHilary Miles Modified over 5 years ago

Similar presentations

Presentation on theme: "A methacholine challenge dose-response study for development of a pharmacodynamic bioequivalence methodology for albuterol metered-dose inhalers  Peter."— Presentation transcript:

1 A methacholine challenge dose-response study for development of a pharmacodynamic bioequivalence methodology for albuterol metered-dose inhalers  Peter S. Creticos, MDa, Wallace P. Adams, PhDb, Brent G. Petty, MDc, Lionel D. Lewis, MBBCh, MDc, Gur Jai Pal Singh, PhDd, Arouna P. Khattignavong, MDa, Justina A. Molzon, MS, JDe, Marilyn N. Martinez, PhDd, Paul S. Lietman, MD, PhDc, Roger L. Williams, MDb  Journal of Allergy and Clinical Immunology  Volume 110, Issue 5, Pages (November 2002) DOI: /mai Copyright © 2002 Mosby, Inc. Terms and Conditions

2 Fig. 1 Posterior Bayesian fitting of PD20 as a function of dose for the 15 study subjects. Abscissa scaling is constant for all plots. Ordinate scaling varies with the observed maximal response of individual subjects. The plots reveal dose-response data with low variability (eg, subject 2) and high variability (eg, subject 13). Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

Download ppt "A methacholine challenge dose-response study for development of a pharmacodynamic bioequivalence methodology for albuterol metered-dose inhalers  Peter."

Similar presentations

Superior biologic activity of the recombinant bee venom allergen hyaluronidase expressed in baculovirus-infected insect cells as compared with Escherichia.

Superior biologic activity of the recombinant bee venom allergen hyaluronidase expressed in baculovirus-infected insect cells as compared with Escherichia.
Efficacy and safety overview of a new inhaled corticosteroid, QVAR (hydrofluoroalkane- beclomethasone extrafine inhalation aerosol), in asthma Jennifer.

Efficacy and safety overview of a new inhaled corticosteroid, QVAR (hydrofluoroalkane- beclomethasone extrafine inhalation aerosol), in asthma Jennifer.
Reducing relative humidity to control the house dust mite Dermatophagoides farinae Larry G. Arlian, PhD, Jacqueline S. Neal, BS, DiAnn L. Vyszenski-Moher,

Reducing relative humidity to control the house dust mite Dermatophagoides farinae Larry G. Arlian, PhD, Jacqueline S. Neal, BS, DiAnn L. Vyszenski-Moher,
W.Travis Cain, MDa, Greg Cable, PhDb, John J. Oppenheimer, MDc 

W.Travis Cain, MDa, Greg Cable, PhDb, John J. Oppenheimer, MDc 
Double-blind placebo-controlled study of the efficacy of oral terfenadine in the treatment of chronic fatigue syndrome  Paul Steinberg, MDa, Bruce E.

Double-blind placebo-controlled study of the efficacy of oral terfenadine in the treatment of chronic fatigue syndrome  Paul Steinberg, MDa, Bruce E.
Kiwi fruit allergy: A new birch pollen–associated food allergy

Kiwi fruit allergy: A new birch pollen–associated food allergy
The effect of hydrolyzed cow's milk formula for allergy prevention in the first year of life: The German Infant Nutritional Intervention Study, a randomized.

The effect of hydrolyzed cow's milk formula for allergy prevention in the first year of life: The German Infant Nutritional Intervention Study, a randomized.
Occupational asthma caused by a natural food colorant derived from Monascus ruber  Olivier Vandenplas, MDa,b, Jean-Marie Caroyer, MDb, Françoise Binard-van.

Occupational asthma caused by a natural food colorant derived from Monascus ruber  Olivier Vandenplas, MDa,b, Jean-Marie Caroyer, MDb, Françoise Binard-van.
Eosinophil cationic protein and histamine after intestinal challenge in patients with cow's milk intolerance  Ulf Bengtsson, MD, PhDa, Tina W. Knutson,

Eosinophil cationic protein and histamine after intestinal challenge in patients with cow's milk intolerance  Ulf Bengtsson, MD, PhDa, Tina W. Knutson,
Kiwi fruit allergy: A new birch pollen–associated food allergy

Kiwi fruit allergy: A new birch pollen–associated food allergy
Allergen vaccination with a liposome-encapsulated extract of Dermatophagoides pteronyssinus : A randomized, double-blind, placebo-controlled trial in.

Allergen vaccination with a liposome-encapsulated extract of Dermatophagoides pteronyssinus : A randomized, double-blind, placebo-controlled trial in.
Protective effect of inhaled budesonide against unlimited airway narrowing to methacholine in atopic patients with asthma  Patrick Booms, MSca, David.

Protective effect of inhaled budesonide against unlimited airway narrowing to methacholine in atopic patients with asthma  Patrick Booms, MSca, David.
Asthma and increased bronchial responsiveness in elite athletes: Atopy and sport event as risk factors  Ilkka J. Helenius, MDa, Heikki O. Tikkanen, MDb,

Asthma and increased bronchial responsiveness in elite athletes: Atopy and sport event as risk factors  Ilkka J. Helenius, MDa, Heikki O. Tikkanen, MDb,
Comparison of once-daily ebastine 20 mg, ebastine 10 mg, loratadine 10 mg, and placebo in the treatment of seasonal allergic rhinitis  Paul H. Ratner,

Comparison of once-daily ebastine 20 mg, ebastine 10 mg, loratadine 10 mg, and placebo in the treatment of seasonal allergic rhinitis  Paul H. Ratner,
Wheat ω-5 gliadin is a major allergen in children with immediate allergy to ingested wheat  Kati Palosuo, MDa,b, Elina Varjonen, MDa, Outi-Maria Kekki,

Wheat ω-5 gliadin is a major allergen in children with immediate allergy to ingested wheat  Kati Palosuo, MDa,b, Elina Varjonen, MDa, Outi-Maria Kekki,
Practice Notes from the AAAI

Practice Notes from the AAAI
Badrul A. Chowdhury, MD, PhD 

Badrul A. Chowdhury, MD, PhD 
Pathophysiology of severe asthma

Pathophysiology of severe asthma
Multicenter, double-blind, placebo-controlled, multiple-challenge evaluation of reported reactions to monosodium glutamate  Raif S. Geha, MDa, Alexa Beiser,

Multicenter, double-blind, placebo-controlled, multiple-challenge evaluation of reported reactions to monosodium glutamate  Raif S. Geha, MDa, Alexa Beiser,
Adverse effects of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors associated with elevated serum IgE and eosinophilia  Carol K. Fosso, MDa,

Adverse effects of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors associated with elevated serum IgE and eosinophilia  Carol K. Fosso, MDa,

Similar presentations

Ads by Google