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Tactile allodynia with activation of dorsal horn neuron in atopy model mice. Tactile allodynia with activation of dorsal horn neuron in atopy model mice.

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Presentation on theme: "Tactile allodynia with activation of dorsal horn neuron in atopy model mice. Tactile allodynia with activation of dorsal horn neuron in atopy model mice."— Presentation transcript:

1 Tactile allodynia with activation of dorsal horn neuron in atopy model mice.
Tactile allodynia with activation of dorsal horn neuron in atopy model mice. Tactile allodynia as determined by von Frey filament test. A, Tactile allodynia in bronchial asthma model mice. Reaction rates of PBS-, Alum-, and O+A-pretreated mice with different stimulation strength of von Frey filaments. Bars filled with different patterns represent different pretreatments before inhalation of OVA. n = 5 for each group. B, Tactile allodynia is also evident in atopic diathesis mice without inhalation of OVA (O+A group). n = 4 for each group. C, Dorsal horn sensory neurons were activated with increased number of FOSB-positive cells only in the bronchial asthma model. D, Quantitative analysis of FOSB-positive cells in the dorsal horns of bronchial asthma model mice. **p < (Tukey's post test after one-way ANOVA). ***p < (Tukey's post test after one-way ANOVA). Ryo Yamasaki et al. J. Neurosci. 2016;36: ©2016 by Society for Neuroscience

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