Presentation is loading. Please wait.

Presentation is loading. Please wait.

Regulation of Bcl-2 family proteins in the hypothalamus of non-diabetic and diabetic IRS2−/− mice. Regulation of Bcl-2 family proteins in the hypothalamus.

Published byMaija Salonen Modified over 5 years ago

Similar presentations

Presentation on theme: "Regulation of Bcl-2 family proteins in the hypothalamus of non-diabetic and diabetic IRS2−/− mice. Regulation of Bcl-2 family proteins in the hypothalamus."— Presentation transcript:

1 Regulation of Bcl-2 family proteins in the hypothalamus of non-diabetic and diabetic IRS2−/− mice.
Regulation of Bcl-2 family proteins in the hypothalamus of non-diabetic and diabetic IRS2−/− mice. Immunoblots probed with antibodies against Bcl-2 (A), Bcl-xL (B), BAD (C), BID (D) and BIM (E) in the hypothalamus of wild-type (WT), non-diabetic IRS2-deficient (ND IRS2−/−) and diabetic IRS2-deficient (D IRS2−/−) mice. (F) Representative immunoblotos for Bcl-2, Bcl-xL, BAD, BID, BIM and GAPDH. Data are presented as means±s.e.m. Statistical significance by ANOVA: *P<0.05 vs WT mice; n=6/group. Eva Baquedano et al. Dis. Model. Mech. 2016;9: © Published by The Company of Biologists Ltd

Download ppt "Regulation of Bcl-2 family proteins in the hypothalamus of non-diabetic and diabetic IRS2−/− mice. Regulation of Bcl-2 family proteins in the hypothalamus."

Similar presentations

Adamtsl2 targeting strategy and validation of inactivation.

Adamtsl2 targeting strategy and validation of inactivation.
VacA does not induce phosphorylation of Src in RPTPα constitutive-knockdown AZ-521 cells. VacA does not induce phosphorylation of Src in RPTPα constitutive-knockdown.

VacA does not induce phosphorylation of Src in RPTPα constitutive-knockdown AZ-521 cells. VacA does not induce phosphorylation of Src in RPTPα constitutive-knockdown.
Total and differential cell counting in the broncho-alveolar lavage of mice exposed to CS or air during 3 or 6 months. Total and differential cell counting.

Total and differential cell counting in the broncho-alveolar lavage of mice exposed to CS or air during 3 or 6 months. Total and differential cell counting.
Representative histological images of aorta from WT, ApoEm/m and ApoE−/− pigs. Representative histological images of aorta from WT, ApoEm/m and ApoE−/−

Representative histological images of aorta from WT, ApoEm/m and ApoE−/− pigs. Representative histological images of aorta from WT, ApoEm/m and ApoE−/−
Tomoregulin-1 improves cardiac pathological changes after pressure overload. Tomoregulin-1 improves cardiac pathological changes after pressure overload.

Tomoregulin-1 improves cardiac pathological changes after pressure overload. Tomoregulin-1 improves cardiac pathological changes after pressure overload.
Discordance and similarity between humans with FA and FA mouse models.

Discordance and similarity between humans with FA and FA mouse models.
Crotonate prevents downregulation of kidney PGC-1α and SIRT3 as well as causing CCL2 upregulation in experimental AKI. AKI was induced by a folic acid.

Crotonate prevents downregulation of kidney PGC-1α and SIRT3 as well as causing CCL2 upregulation in experimental AKI. AKI was induced by a folic acid.
Crotonate increases histone crotonylation in mouse kidney.

Crotonate increases histone crotonylation in mouse kidney.
Effect of OLHHA on the protein expression of relevant enzymes and factors related to lipid metabolism in the liver of obese Zucker rats. Effect of OLHHA.

Effect of OLHHA on the protein expression of relevant enzymes and factors related to lipid metabolism in the liver of obese Zucker rats. Effect of OLHHA.
Concentration of biomarkers of haemostasis.

Concentration of biomarkers of haemostasis.
TP53 western blot of primary cultured tail cells from both wild-type (WT) and Tp53Δ11/Δ11 (−/−) rats. TP53 western blot of primary cultured tail cells.

TP53 western blot of primary cultured tail cells from both wild-type (WT) and Tp53Δ11/Δ11 (−/−) rats. TP53 western blot of primary cultured tail cells.
Tomoregulin-1 inhibits the TGFβ non-canonical (TAK1-JNK) pathways after pressure overload. Tomoregulin-1 inhibits the TGFβ non-canonical (TAK1-JNK) pathways.

Tomoregulin-1 inhibits the TGFβ non-canonical (TAK1-JNK) pathways after pressure overload. Tomoregulin-1 inhibits the TGFβ non-canonical (TAK1-JNK) pathways.
Expression of tomoregulin-1 in wild-type and cardiac hypertrophy mouse myocardium. Expression of tomoregulin-1 in wild-type and cardiac hypertrophy mouse.

Expression of tomoregulin-1 in wild-type and cardiac hypertrophy mouse myocardium. Expression of tomoregulin-1 in wild-type and cardiac hypertrophy mouse.
Survival and telomere length of G2tert−/− zebrafish in a p53−/− background. Survival and telomere length of G2tert−/− zebrafish in a p53−/− background.

Survival and telomere length of G2tert−/− zebrafish in a p53−/− background. Survival and telomere length of G2tert−/− zebrafish in a p53−/− background.
Hypoacidity, anemia and hypergastrinemia in KI/KI mice.

Hypoacidity, anemia and hypergastrinemia in KI/KI mice.
Secondary storage of GM2 ganglioside and cholesterol in Fuca1-deficient mice. Secondary storage of GM2 ganglioside and cholesterol in Fuca1-deficient mice.

Secondary storage of GM2 ganglioside and cholesterol in Fuca1-deficient mice. Secondary storage of GM2 ganglioside and cholesterol in Fuca1-deficient mice.
TWEAK downregulates SIRT3 in cultured tubular cells and this is prevented by crotonate. TWEAK downregulates SIRT3 in cultured tubular cells and this is.

TWEAK downregulates SIRT3 in cultured tubular cells and this is prevented by crotonate. TWEAK downregulates SIRT3 in cultured tubular cells and this is.
Obesity affected the metabolic response to stroke.

Obesity affected the metabolic response to stroke.
Expression data confirm and extend existing knowledge

Expression data confirm and extend existing knowledge
Elevated pAkt level in ptena−/−ptenb−/− mutants is suppressed by LY294002 and to a lesser extent by sunitinib. Elevated pAkt level in ptena−/−ptenb−/−

Elevated pAkt level in ptena−/−ptenb−/− mutants is suppressed by LY and to a lesser extent by sunitinib. Elevated pAkt level in ptena−/−ptenb−/−

Similar presentations

Ads by Google