Presentation is loading. Please wait.

Presentation is loading. Please wait.

Clinical and immunologic variables in skin of patients with atopic eczema and either positive or negative atopy patch test reactions  Elisabeth G. Langeveld-Wildschut,

Similar presentations


Presentation on theme: "Clinical and immunologic variables in skin of patients with atopic eczema and either positive or negative atopy patch test reactions  Elisabeth G. Langeveld-Wildschut,"— Presentation transcript:

1 Clinical and immunologic variables in skin of patients with atopic eczema and either positive or negative atopy patch test reactions  Elisabeth G. Langeveld-Wildschut, MD, PhDa, Piet L.B. Bruijnzeel, MD, PhDb, Geert C. Mudde, PhDc, Coraline Versluisa, Adrie G. Van Ieperen-Van Dijka, Ilse C. Biharia, Edward F. Knol, PhDa, Theo Thepen, PhDa, Carla A.F.M. Bruijnzeel-Koomen, MD, PhDa, Frank C. van Reijsen, PhDa  Journal of Allergy and Clinical Immunology  Volume 105, Issue 5, Pages (May 2000) DOI: /mai Copyright © 2000 Mosby, Inc. Terms and Conditions

2 Fig. 1 Number of CD3+, CD25+, and EG2+ cells per square millimeter in the dermis of normal control subjects (NC) , atopic control subjects (AC) , patients with AE and negative APT reactions 0 and 24 hours after patch testing (APT- AE) , and patients with AE and positive APT reactions 0 and 24 hours after patch testing (APT+ AE) . Results are shown as mean values ± SEM of 6 different individuals per group. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2000 Mosby, Inc. Terms and Conditions

3 Fig. 2 Number of IgE+ and unoccupied FcϵRI+ cells in epidermis (epi , per 200 basal membrane cells) and dermis (der , per square millimeter) in normal control subjects (NC) , atopic control subjects (AC) , patients with AE and negative APT reactions (APT- AE) , and patients with AE and positive APT reactions (APT+ AE) . Biopsy specimens were obtained from untreated skin. Results are shown as mean values ± SEM of 10 different individuals per group. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2000 Mosby, Inc. Terms and Conditions

4 Fig. 3 Binding of anti-IgE in skin of patients with AE and negative APT reactions (A ) and patients with AE and positive APT reactions (B ). Biopsy specimens were obtained from untreated skin. Two representative photomicrographs are shown (objective magnification 20×). Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2000 Mosby, Inc. Terms and Conditions


Download ppt "Clinical and immunologic variables in skin of patients with atopic eczema and either positive or negative atopy patch test reactions  Elisabeth G. Langeveld-Wildschut,"

Similar presentations


Ads by Google