1. It Takes Two Binding Sites for Calcineurin and NFAT to Tango
Jun O. Liu, Benjamin A. Nacev, Jing Xu, Shridhar Bhat 
Molecular Cell 
Volume 33, Issue 6, Pages (March 2009)
DOI: /j.molcel
Copyright © 2009 Elsevier Inc. Terms and Conditions

2. Figure 1 The Sites of Interactions between Calcineurin and NFAT
Shown are the crystal structure of calcineurin and the domain structures of the NFAT regulatory domain. Color codes: blue, the catalytic subunit of calcineurin lacking the C terminus; green, the regulatory domain of calcineurin; yellow, the PxIxIT motif of NFAT and its binding site on the catalytic domain of calcineurin; orange, the regulatory domain of NFAT and the active site of calcineurin; pink, the LxVP motif of NFAT and its binding site on the composite surface of the two subunits of calcineurin; red, NFAT phosphorylation sites.
Molecular Cell  , DOI: ( /j.molcel )
Copyright © 2009 Elsevier Inc. Terms and Conditions