1. Headache frequency after medication withdrawal in medication-overuse headache.
Headache frequency after medication withdrawal in medication-overuse headache. This Danish study of people with probable medication-overuse headache (175 patients) compared the frequency of headache before and after complete drug withdrawal and then after drug management in the clinic. Between the initial visit (before withdrawal) and discharge from clinic post-withdrawal, there was a mean reduction in headache frequency across the cohort of 46% (p<0.0001). The values represent mean reduction in headache days per month with median and range in brackets. *p< (adapted from Zeeburg et al44).
Alex J Sinclair et al. Pract Neurol 2015;15:
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