Presentation is loading. Please wait.

Presentation is loading. Please wait.

Next-Generation Experimentation with Self-Driving Laboratories

Published byCory Smith Modified over 5 years ago

Similar presentations

Presentation on theme: "Next-Generation Experimentation with Self-Driving Laboratories"— Presentation transcript:

1 Next-Generation Experimentation with Self-Driving Laboratories
Florian Häse, Loïc M. Roch, Alán Aspuru-Guzik  Trends in Chemistry  Volume 1, Issue 3, Pages (June 2019) DOI: /j.trechm Copyright © 2019 Elsevier Inc. Terms and Conditions

2 Figure 1 Experiment Planning Strategies. The experiment planning procedure aims to identify experimental conditions for which the resulting properties satisfy desired targets. (A) High-throughput screening iterations consist of scanning a set of a priori selected conditions without refinements. (B) Optimization strategies that plan experiments based on a fixed number of prior iterations. (C) Search strategies that plan experiments based on a surrogate model constructed from all prior experiments. Trends in Chemistry 2019 1, DOI: ( /j.trechm ) Copyright © 2019 Elsevier Inc. Terms and Conditions

3 Figure 2 The Closed-Loop Approach (Box 1). The closed-loop approach uses an experiment planning algorithm based on machine learning (ML) and a number of automated robotics platforms to execute experiments. Several ML methods can be used to construct surrogate models, such as Bayesian neural networks (illustrated earlier), Gaussian processes, or random forests. A control software schedules experiments and directs experimental feedback. Trends in Chemistry 2019 1, DOI: ( /j.trechm ) Copyright © 2019 Elsevier Inc. Terms and Conditions

4 Figure 3 The Modules Involved in Next-Generation Self-Driving Laboratories. They are empowered by artificial intelligence for experiment planning, device scheduling, data analysis, and researcher communication. A control software (top right) orchestrates individual modules of the self-driving laboratories. Modules highlighted in gray are directly involved in the experimentation process, either to plan new experiments or to execute recommended experiments. Modules highlighted in yellow improve the user-friendliness and practicality of self-driving laboratories and facilitate long-term data storage or communication with researchers. Trends in Chemistry 2019 1, DOI: ( /j.trechm ) Copyright © 2019 Elsevier Inc. Terms and Conditions

5 Figure I Opportunities for Enriching Features toward User-Friendliness. Recent developments in the AI community provide tools which can improve the practicality of a self-driving laboratory. Trends in Chemistry 2019 1, DOI: ( /j.trechm ) Copyright © 2019 Elsevier Inc. Terms and Conditions

Download ppt "Next-Generation Experimentation with Self-Driving Laboratories"

Similar presentations

Expectation Modulates Neural Responses to Pleasant and Aversive Stimuli in Primate Amygdala Marina A. Belova, Joseph J. Paton, Sara E. Morrison, C. Daniel.

Expectation Modulates Neural Responses to Pleasant and Aversive Stimuli in Primate Amygdala Marina A. Belova, Joseph J. Paton, Sara E. Morrison, C. Daniel.
Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages 241-253 (March 2014) DOI: 10.1016/j.cell.2014.02.012 Copyright.

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.
What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages 20-44 (January 2014) DOI: 10.1016/j.cell.2013.12.012.

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell
10 - 1 Copyright © 2006, The McGraw-Hill Companies, Inc. All rights reserved. Decision Support Systems Chapter 10.

Copyright © 2006, The McGraw-Hill Companies, Inc. All rights reserved. Decision Support Systems Chapter 10.
Advances in shaking technologies Wolf Klöckner, Jochen Büchs Trends in Biotechnology Volume 30, Issue 6, Pages 307-314 (June 2012) DOI: 10.1016/j.tibtech.2012.03.001.

Advances in shaking technologies Wolf Klöckner, Jochen Büchs Trends in Biotechnology Volume 30, Issue 6, Pages (June 2012) DOI: /j.tibtech
The Pathobiology of Vascular Dementia Costantino Iadecola Neuron Volume 80, Issue 4, Pages 844-866 (November 2013) DOI: 10.1016/j.neuron.2013.10.008 Copyright.

The Pathobiology of Vascular Dementia Costantino Iadecola Neuron Volume 80, Issue 4, Pages (November 2013) DOI: /j.neuron Copyright.
How do emotion and motivation direct executive control? Luiz Pessoa Trends in Cognitive Sciences Volume 13, Issue 4, Pages 160-166 (April 2009) DOI: 10.1016/j.tics.2009.01.006.

How do emotion and motivation direct executive control? Luiz Pessoa Trends in Cognitive Sciences Volume 13, Issue 4, Pages (April 2009) DOI: /j.tics
Contour Saliency in Primary Visual Cortex Wu Li, Valentin Piëch, Charles D. Gilbert Neuron Volume 50, Issue 6, Pages 951-962 (June 2006) DOI: 10.1016/j.neuron.2006.04.035.

Contour Saliency in Primary Visual Cortex Wu Li, Valentin Piëch, Charles D. Gilbert Neuron Volume 50, Issue 6, Pages (June 2006) DOI: /j.neuron
Two views of brain function Marcus E. Raichle Trends in Cognitive Sciences Volume 14, Issue 4, Pages 180-190 (April 2010) DOI: 10.1016/j.tics.2010.01.008.

Two views of brain function Marcus E. Raichle Trends in Cognitive Sciences Volume 14, Issue 4, Pages (April 2010) DOI: /j.tics
IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages 389-391 (October.

IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.
Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages 248-252 (April 2010) DOI: 10.1016/j.cmet.2010.03.008 Copyright © 2010.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.
Synapse-Specific Adaptations to Inactivity in Hippocampal Circuits Achieve Homeostatic Gain Control while Dampening Network Reverberation Jimok Kim, Richard.

Synapse-Specific Adaptations to Inactivity in Hippocampal Circuits Achieve Homeostatic Gain Control while Dampening Network Reverberation Jimok Kim, Richard.
Germline Energetics, Aging, and Female Infertility Jonathan L. Tilly, David A. Sinclair Cell Metabolism Volume 17, Issue 6, Pages 838-850 (June 2013) DOI:

Germline Energetics, Aging, and Female Infertility Jonathan L. Tilly, David A. Sinclair Cell Metabolism Volume 17, Issue 6, Pages (June 2013) DOI:
Cell-to-Cell Transfer of M. tuberculosis Antigens Optimizes CD4 T Cell Priming Smita Srivastava, Joel D. Ernst Cell Host & Microbe Volume 15, Issue 6,

Cell-to-Cell Transfer of M. tuberculosis Antigens Optimizes CD4 T Cell Priming Smita Srivastava, Joel D. Ernst Cell Host & Microbe Volume 15, Issue 6,
Recognizing Protein-Ligand Binding Sites by Global Structural Alignment and Local Geometry Refinement Ambrish Roy, Yang Zhang Structure Volume 20, Issue.

Recognizing Protein-Ligand Binding Sites by Global Structural Alignment and Local Geometry Refinement Ambrish Roy, Yang Zhang Structure Volume 20, Issue.
Intelligent software for laboratory automation

Intelligent software for laboratory automation
We teach ATM Networks to Think

We teach ATM Networks to Think
Machine Learning for High-Throughput Stress Phenotyping in Plants

Machine Learning for High-Throughput Stress Phenotyping in Plants
Merging of Long-Term Memories in an Insect

Merging of Long-Term Memories in an Insect
Volume 1, Issue 1, Pages (June 2007)

Volume 1, Issue 1, Pages (June 2007)

Similar presentations

Ads by Google