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The Gene Encoding Nicastrin, a Major γ-Secretase Component, Modifies Risk for Familial Early-Onset Alzheimer Disease in a Dutch Population-Based Sample 

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Presentation on theme: "The Gene Encoding Nicastrin, a Major γ-Secretase Component, Modifies Risk for Familial Early-Onset Alzheimer Disease in a Dutch Population-Based Sample "— Presentation transcript:

1 The Gene Encoding Nicastrin, a Major γ-Secretase Component, Modifies Risk for Familial Early-Onset Alzheimer Disease in a Dutch Population-Based Sample  Bart Dermaut, Jessie Theuns, Kristel Sleegers, Hiroshi Hasegawa, Marleen Van den Broeck, Krist'l Vennekens, Ellen Corsmit, Peter St. George-Hyslop, Marc Cruts, Cornelia M. van Duijn, Christine Van Broeckhoven  The American Journal of Human Genetics  Volume 70, Issue 6, Pages (June 2002) DOI: /340732 Copyright © 2002 The American Society of Human Genetics Terms and Conditions

2 Figure 1 Genomic structure of NCSTN and major SNP haplotypes, with their estimated frequencies in 78 patients with familial EOAD. SNPs used for case-control association analysis are in boldface. The American Journal of Human Genetics  , DOI: ( /340732) Copyright © 2002 The American Society of Human Genetics Terms and Conditions


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