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A. Khwaja, C.C. Sharpe, M. Noor, B.M. Hendry  Kidney International 

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Presentation on theme: "A. Khwaja, C.C. Sharpe, M. Noor, B.M. Hendry  Kidney International "— Presentation transcript:

1 The role of geranylgeranylated proteins in human mesangial cell proliferation 
A. Khwaja, C.C. Sharpe, M. Noor, B.M. Hendry  Kidney International  Volume 70, Issue 7, Pages (October 2006) DOI: /sj.ki Copyright © 2006 International Society of Nephrology Terms and Conditions

2 Figure 2 Study of apoptosis. (a, c) Proapoptotic effects of 10μM lovastatin and (b, d) 10–20μM GGTI 298 in serum- and PDGF-stimulated HMCs. Apoptosis was determined by Hoechst and propidium iodide staining. Co-incubation of lovastatin with 7.5μM GGPP reduces the proapoptoic effects of lovastatin. The error bars are s.e.m., n=3. *P<0.05 and ***P<0.001 with respect to vehicle-treated cells. Kidney International  , DOI: ( /sj.ki ) Copyright © 2006 International Society of Nephrology Terms and Conditions


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